Interactor 1: RIR2 (P69924)
Ribonucleoside-diphosphate reductase 1 subunit beta (EC 1.17.4.1) (Protein B2) (Protein R2) (Ribonucleotide reductase 1)
Gene: nrdB

Interactor 2: RIR2 (P69924)
Ribonucleoside-diphosphate reductase 1 subunit beta (EC 1.17.4.1) (Protein B2) (Protein R2) (Ribonucleotide reductase 1)
Gene: nrdB

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.888

The method score is based on:

Property Details
Experiments 17726094, 22160671, 19834901, 16858726
Identification Methods molecular sieving, cosedimentation in solution, x ray scattering, two hybrid array, blue native page
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ribonuc_red_sm~Ribonuc_red_sm
Common GO terms GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005506 - iron ion binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005971 - ribonucleoside-diphosphate reductase complex
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 376
Ec

1 376
+ Hs
+ Hs
+ Vv
+ Hs
+ Sc
+ Ce
+ Sc
+ Sc
+ Hh
+ Hh
+ Hh
+ Ha
+ Ec
+ Mp
+ Mt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024