HitPredict

Interactor 1: HDAC2 (P70288)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-) (YY1 transcription factor-binding protein)
Gene: HDAC2

Interactor 2: Q5DTP7 (Q5DTP7)
DNA helicase (EC 3.6.4.12)
Gene: Chd4

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	23624931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 488 Mm			1 1945
+	Hs
		1059770 HDAC2_HUMAN (1-488): 0: 707: 99.39		CHD4_HUMAN (22-1945): 0: 1719: 97.97
+	Hs
		1038382 HDAC1_HUMAN (1-446): 0: 643: 89.24		CHD4_HUMAN (22-1945): 0: 1719: 97.97
+	Mm
		140286 HDAC1_MOUSE (1-446): 0: 647: 89.46		CHD4_MOUSE (22-1933): 0: 1696: 99.32
+	Hs
		1018617 HDAC2_HUMAN (1-488): 0: 707: 99.39		CHD3_HUMAN (40-1938): 0: 1619: 67.25
+	Hs
		1255037 HDAC2_HUMAN (1-488): 0: 707: 99.39		CHD5_HUMAN (42-1942): 0: 1617: 69.20
+	Mm
		56900 HDAC2_MOUSE (1-488): 0: 706: 100.00		CHD5_MOUSE (110-1945): 0: 1615: 70.14
+	Hs
		1018465 HDAC1_HUMAN (1-446): 0: 643: 89.24		CHD3_HUMAN (40-1938): 0: 1619: 67.25
+	Mm
		56897 HDAC1_MOUSE (1-446): 0: 647: 89.46		CHD5_MOUSE (110-1945): 0: 1615: 70.14
+	Hs
		1038563 HDAC1_HUMAN (1-446): 0: 643: 89.24		CHD5_HUMAN (42-1942): 0: 1617: 69.20
+	Dm
		332806 HDAC1_DROME (5-472): 0: 654: 77.71		CHDM_DROME (106-1937): 0: 1404: 52.90
+	Ce
		184848 HDA1_CAEEL (7-456): 0: 596: 64.02		CHD3_CAEEL (161-1942): 0: 1240: 43.36
+	Ce
		104624 HDA1_CAEEL (7-456): 0: 596: 64.02		LE418_CAEEL (105-1936): 0: 1208: 41.62
+	Hs
		229453 HDAC2_HUMAN (1-488): 0: 707: 99.39		SMCA5_HUMAN (597-1651): 0: 789: 26.07
+	Dm
		1097627 HDAC1_DROME (5-472): 0: 654: 77.71		ISWI_DROME (642-1660): 0: 773: 26.29
+	Hs
		1038730 HDAC1_HUMAN (1-446): 0: 643: 89.24		CHD8_HUMAN (6-1766): 0: 760: 21.30
+	Hs
		151408 HDAC1_HUMAN (1-446): 0: 643: 89.24		CHD1_HUMAN (525-1756): 0: 758: 29.44
+	Sp
		140711 PHD1_SCHPO (7-411): 0: 519: 52.56		HRP1_SCHPO (551-1706): 0: 811: 28.96
+	Mm
		59025 HDAC4_MOUSE (1-377): 7.49e-132: 409: 23.89		CHD6_MOUSE (237-1766): 0: 829: 24.26
+	Sp
		140477 PHD1_SCHPO (7-411): 0: 519: 52.56		HRP3_SCHPO (530-1756): 0: 699: 26.62
+	Mm
		1000158 HDAC4_MOUSE (1-377): 7.49e-132: 409: 23.89		CHD8_MOUSE (6-1766): 0: 766: 21.16