Interactor 1: IRF7 (P70434)
Interferon regulatory factor 7 (IRF-7)
Gene: IRF7

Interactor 2: IKKA (Q60680)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA)
Gene: Chuk

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 0.60 0.515

The method score is based on:

Property Details
Experiments 16612387
Identification Methods anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0032727 - positive regulation of interferon-alpha production
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0051607 - defense response to virus
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 457
Mm

1 745
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024