HitPredict

Interactor 1: SET (Q01105)
Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I)
Gene: SET

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29104064
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 290 Hs			1 136
+	Hs
		998219 SET_HUMAN (1-236): 1.98e-87: 264: 100.00		H31_HUMAN (1-136): 3.1e-62: 188: 99.27
+	Hs
		1016779 SET_HUMAN (1-236): 1.98e-87: 264: 100.00		H33_HUMAN (1-136): 2.57e-61: 186: 97.06
+	Hs
		1029303 SET_HUMAN (1-236): 1.98e-87: 264: 100.00		H31T_HUMAN (1-136): 1.38e-61: 186: 96.32
+	Hs
		1162074 TSYL4_HUMAN (31-235): 9.16e-84: 259: 36.59		H31T_HUMAN (1-136): 1.38e-61: 186: 96.32
+	Hs
		998496 TSYL5_HUMAN (2-257): 1.22e-80: 251: 32.69		H31_HUMAN (1-136): 3.1e-62: 188: 99.27
+	Hs
		1016993 TSYL5_HUMAN (2-257): 1.22e-80: 251: 32.69		H33_HUMAN (1-136): 2.57e-61: 186: 97.06
+	Hs
		998797 TSYL2_HUMAN (34-283): 3.72e-76: 246: 31.20		H31_HUMAN (1-136): 3.1e-62: 188: 99.27
+	Hs
		1162017 NP1L4_HUMAN (4-242): 2.1e-75: 236: 18.81		H31T_HUMAN (1-136): 1.38e-61: 186: 96.32
+	Hs
		1258925 NP1L4_HUMAN (4-242): 2.1e-75: 236: 18.81		H32_HUMAN (1-136): 6.24e-61: 185: 100.00
+	Hs
		936711 NP1L1_HUMAN (2-278): 6.65e-74: 233: 18.41		H31_HUMAN (1-136): 3.1e-62: 188: 99.27
+	Hs
		936786 NP1L1_HUMAN (2-278): 6.65e-74: 233: 18.41		H32_HUMAN (1-136): 6.24e-61: 185: 100.00
+	At
		947422 NAP1B_ARATH (29-238): 1.62e-68: 219: 23.66		H33_ARATH (1-136): 7.79e-62: 187: 96.32
+	At
		947421 NAP1A_ARATH (29-239): 1.76e-68: 218: 23.49		H33_ARATH (1-136): 7.79e-62: 187: 96.32
+	At
		947413 NAP1C_ARATH (29-239): 1.43e-67: 216: 24.34		H33_ARATH (1-136): 7.79e-62: 187: 96.32
+	At
		947625 NAP1B_ARATH (29-238): 1.62e-68: 219: 23.66		H31_ARATH (1-136): 1.71e-60: 184: 97.06
+	At
		947624 NAP1A_ARATH (29-239): 1.76e-68: 218: 23.49		H31_ARATH (1-136): 1.71e-60: 184: 97.06
+	At
		947618 NAP1C_ARATH (29-239): 1.43e-67: 216: 24.34		H31_ARATH (1-136): 1.71e-60: 184: 97.06
+	Dm
		381746 Q9W1G7_DROME (18-238): 3.69e-66: 212: 20.54		H3_DROME (1-136): 6.24e-61: 185: 100.00
+	Sc
		670320 NAP1_YEAST (38-286): 1.23e-34: 131: 21.54		H3_YEAST (1-136): 1.23e-55: 171: 88.97
+	Sc
		670248 NAP1_YEAST (38-286): 1.23e-34: 131: 21.54		CENPA_YEAST (18-134): 2.58e-43: 143: 56.67