HitPredict

Interactor 1: SYJ2B (P57105)
Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25)
Gene: SYNJ2BP

Interactor 2: LRP8 (Q14114)
Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2)
Gene: LRP8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	10827173
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 145 Hs			1 963
+	Hs
		1006061 DLG4_HUMAN (3-142): 2.02e-28: 110: 31.94		LRP8_HUMAN (1-963): 0: 819: 100.00
+	Dm
		119052 M9NFI9_DROME (14-110): 8.18e-30: 115: 32.65		Q9VBN2_DROME (5-256): 8.35e-29: 126: 24.47
+	Mm
		1223698 DLG4_MOUSE (3-142): 2.04e-28: 110: 31.94		LRP8_MOUSE (5-333): 9.04e-30: 129: 26.82
+	Hs
		944376 SYJ2B_HUMAN (1-145): 2.14e-47: 151: 100.00		LRP2_HUMAN (222-440): 1.56e-11: 71: 17.77
+	Mm
		1362473 SYJ2B_MOUSE (1-145): 1.78e-46: 149: 91.03		LRP1_MOUSE (699-897): 1.64e-09: 64.5: 9.85
+	Hs
		944378 SYJ2B_HUMAN (1-145): 2.14e-47: 151: 100.00		LRP1_HUMAN (700-897): 7.7e-09: 62.2: 8.91
+	Mm
		59788 SYJ2B_MOUSE (1-145): 1.78e-46: 149: 91.03		LRP2_MOUSE (692-899): 1.87e-09: 64.1: 11.39
+	Mm
		73130 DLG4_MOUSE (3-142): 2.04e-28: 110: 31.94		B1AXJ3_MOUSE (5-228): 8.94e-22: 103: 17.87
+	Dm
		119454 M9NFI9_DROME (14-110): 8.18e-30: 115: 32.65		Q9W4Y3_DROME (151-333): 1.13e-11: 71.6: 28.00
+	Mm
		1365303 SNTG2_MOUSE (3-144): 3.11e-31: 118: 23.38		LRP1B_MOUSE (700-898): 1.38e-09: 64.5: 7.43
+	Hs
		1022613 DLG2_HUMAN (6-142): 1.93e-28: 111: 29.79		LRP2_HUMAN (222-440): 1.56e-11: 71: 17.77
+	Mm
		59442 A2AKD7_MOUSE (7-141): 3.74e-28: 109: 25.00		NID1_MOUSE (7-239): 4.44e-12: 72.6: 12.96
+	Hs
		1006045 DLG4_HUMAN (3-142): 2.02e-28: 110: 31.94		LRP2_HUMAN (222-440): 1.56e-11: 71: 17.77
+	Mm
		1223693 DLG4_MOUSE (3-142): 2.04e-28: 110: 31.94		LRP1_MOUSE (699-897): 1.64e-09: 64.5: 9.85
+	Mm
		59782 DLG4_MOUSE (3-142): 2.04e-28: 110: 31.94		LRP2_MOUSE (692-899): 1.87e-09: 64.1: 11.39
+	Hs
		1006053 DLG4_HUMAN (3-142): 2.02e-28: 110: 31.94		LRP1_HUMAN (700-897): 7.7e-09: 62.2: 8.91
+	Hs
		1022637 DLG3_HUMAN (1-118): 4.7e-25: 101: 39.83		LRP2_HUMAN (222-440): 1.56e-11: 71: 17.77