Interactor 1: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Interactor 2: DCR1C (Q96SD1)
Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein) (Protein A-SCID) (SNM1 homolog C) (hSNM1C) (SNM1-like protein)
Gene: DCLRE1C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.750

The method score is based on:

Property Details
Experiments 11955432, 15456891, 16857680, 31900314, 33961781, 15936993, 22529269
Identification Methods pull down, enzymatic study, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000723 - telomere maintenance
GO:0005654 - nucleoplasm
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0070419 - nonhomologous end joining complex
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 4128
Hs

1 692
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024