Interactor 1: LEG9 (O00182)
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
Gene: LGALS9

Interactor 2: HAVR2 (Q8TDQ0)
Hepatitis A virus cellular receptor 2 (HAVcr-2) (T-cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T-cell immunoglobulin mucin receptor 3) (TIM-3) (T-cell membrane protein 3) (CD antigen CD366)
Gene: HAVCR2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23967307
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Gal-bind_lectin~V-set
Common GO terms GO:0002519 - natural killer cell tolerance induction
GO:0006954 - inflammatory response
GO:0010629 - negative regulation of gene expression
GO:0032689 - negative regulation of type II interferon production
GO:0032720 - negative regulation of tumor necrosis factor production
and 6 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 355
Hs

1 301
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024