HitPredict

Interactor 1: M3K9 (P80192)
Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)
Gene: MAP3K9

Interactor 2: HPCA (P84074)
Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2)
Gene: HPCA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	33961781, 36736316
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_1~Pkinase, EF-hand_7~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1104 Hs			1 193
+	Hs
		740653 M3K9_HUMAN (1-1104): 0: 794: 100.00		HPCL1_HUMAN (1-193): 4.46e-58: 182: 94.30
+	Hs
		906758 M3K9_HUMAN (1-1104): 0: 794: 100.00		NCS1_HUMAN (1-187): 2.94e-46: 152: 58.82
+	Hs
		740655 M3K10_HUMAN (44-1086): 0: 584: 52.04		HPCL1_HUMAN (1-193): 4.46e-58: 182: 94.30
+	Hs
		950449 M3K10_HUMAN (44-1086): 0: 584: 52.04		HPCA_HUMAN (1-193): 4.95e-56: 177: 100.00
+	Hs
		740665 M3K21_HUMAN (56-1104): 0: 575: 48.30		HPCL1_HUMAN (1-193): 4.46e-58: 182: 94.30
+	Hs
		901307 M3K21_HUMAN (56-1104): 0: 575: 48.30		NCALD_HUMAN (1-193): 3.31e-56: 177: 88.08
+	Hs
		950455 M3K21_HUMAN (56-1104): 0: 575: 48.30		HPCA_HUMAN (1-193): 4.95e-56: 177: 100.00
+	Hs
		906765 M3K21_HUMAN (56-1104): 0: 575: 48.30		NCS1_HUMAN (1-187): 2.94e-46: 152: 58.82
+	Hs
		740661 M3K11_HUMAN (42-905): 8.76e-144: 454: 44.66		HPCL1_HUMAN (1-193): 4.46e-58: 182: 94.30
+	Hs
		901304 M3K11_HUMAN (42-905): 8.76e-144: 454: 44.66		NCALD_HUMAN (1-193): 3.31e-56: 177: 88.08
+	Hs
		950452 M3K11_HUMAN (42-905): 8.76e-144: 454: 44.66		HPCA_HUMAN (1-193): 4.95e-56: 177: 100.00
+	Hs
		906763 M3K11_HUMAN (42-905): 8.76e-144: 454: 44.66		NCS1_HUMAN (1-187): 2.94e-46: 152: 58.82