HitPredict

Interactor 1: LRP2 (P98164)
Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)
Gene: LRP2

Interactor 2: ZFP41 (Q8N8Y5)
Zinc finger protein 41 homolog (Zfp-41)
Gene: ZFP41

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 4655 Hs			1 198
+	Hs
		485342 LRP2_HUMAN (1-4655): 0: 3803: 100.00		GLI4_HUMAN (3-196): 1.15e-68: 215: 36.32
+	Hs
		1237971 SORL_HUMAN (166-470): 5.79e-19: 98: 16.82		ZFP41_HUMAN (1-198): 1.1e-92: 270: 100.00
+	Hs
		254278 LRP4_HUMAN (3839-4093): 6.21e-15: 84.9: 22.90		ZN383_HUMAN (18-198): 9.34e-90: 272: 36.17
+	Hs
		351089 LDLR_HUMAN (927-1187): 1.96e-15: 86: 17.65		ZFP41_HUMAN (1-198): 1.1e-92: 270: 100.00
+	Hs
		254277 LRP4_HUMAN (3839-4093): 6.21e-15: 84.9: 22.90		ZFP41_HUMAN (1-198): 1.1e-92: 270: 100.00
+	Hs
		1223925 SORL_HUMAN (166-470): 5.79e-19: 98: 16.82		ZNF34_HUMAN (6-198): 3.17e-79: 247: 36.00
+	Hs
		270315 LRP6_HUMAN (3113-3241): 3.94e-09: 65.6: 16.30		ZN383_HUMAN (18-198): 9.34e-90: 272: 36.17
+	Hs
		258331 LRP5_HUMAN (3071-3230): 8.89e-09: 64.5: 12.42		ZN383_HUMAN (18-198): 9.34e-90: 272: 36.17
+	Hs
		992686 LRP1_HUMAN (1102-1387): 4.45e-09: 65.6: 13.59		ZFP41_HUMAN (1-198): 1.1e-92: 270: 100.00
+	Hs
		1237983 LRP1B_HUMAN (4-204): 6.71e-09: 64.9: 16.16		ZFP41_HUMAN (1-198): 1.1e-92: 270: 100.00
+	Hs
		254273 LRP4_HUMAN (3839-4093): 6.21e-15: 84.9: 22.90		ZNF34_HUMAN (6-198): 3.17e-79: 247: 36.00
+	Hs
		1237395 SORL_HUMAN (166-470): 5.79e-19: 98: 16.82		ZN713_HUMAN (57-198): 1.21e-69: 220: 45.78
+	Hs
		485379 SORL_HUMAN (166-470): 5.79e-19: 98: 16.82		GLI4_HUMAN (3-196): 1.15e-68: 215: 36.32
+	Hs
		485414 LRP1B_HUMAN (4-204): 6.71e-09: 64.9: 16.16		GLI4_HUMAN (3-196): 1.15e-68: 215: 36.32
+	Hs
		254304 LRP4_HUMAN (3839-4093): 6.21e-15: 84.9: 22.90		ZN214_HUMAN (55-198): 1.41e-38: 141: 30.99
+	Hs
		254280 LRP4_HUMAN (3839-4093): 6.21e-15: 84.9: 22.90		ZN248_HUMAN (5-198): 2.28e-23: 98.4: 21.20
+	Hs
		270295 LRP6_HUMAN (3113-3241): 3.94e-09: 65.6: 16.30		ZKSC8_HUMAN (1-35): 9.66e-12: 64.9: 22.22