HitPredict

Interactor 1: XIAP (P98170)
E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP)
Gene: XIAP

Interactor 2: UB2J2 (Q8N2K1)
Ubiquitin-conjugating enzyme E2 J2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J2) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE-2)
Gene: UBE2J2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	19549727
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 497 Hs			1 259
+	Hs
		957802 XIAP_HUMAN (1-497): 0: 569: 100.00		UB2D4_HUMAN (12-156): 2.24e-67: 207: 24.16
+	Hs
		849308 XIAP_HUMAN (1-497): 0: 569: 100.00		UB2D1_HUMAN (12-156): 3.85e-66: 204: 24.16
+	Hs
		919707 XIAP_HUMAN (1-497): 0: 569: 100.00		UB2D2_HUMAN (12-156): 3.65e-66: 204: 22.82
+	Hs
		895777 XIAP_HUMAN (1-497): 0: 569: 100.00		UB2D3_HUMAN (12-156): 2.8e-65: 201: 22.15
+	Hs
		957765 XIAP_HUMAN (1-497): 0: 569: 100.00		UB2E2_HUMAN (1-157): 3.56e-61: 193: 25.47
+	Hs
		851802 XIAP_HUMAN (1-497): 0: 569: 100.00		UB2E1_HUMAN (1-157): 7.51e-61: 192: 24.85
+	Hs
		828984 XIAP_HUMAN (1-497): 0: 569: 100.00		UBE2A_HUMAN (10-157): 3.88e-56: 178: 26.32
+	Hs
		849322 BIRC2_HUMAN (3-497): 9.73e-82: 267: 23.31		UB2D1_HUMAN (12-156): 3.85e-66: 204: 24.16
+	Hs
		919722 BIRC2_HUMAN (3-497): 9.73e-82: 267: 23.31		UB2D2_HUMAN (12-156): 3.65e-66: 204: 22.82
+	Hs
		895788 BIRC2_HUMAN (3-497): 9.73e-82: 267: 23.31		UB2D3_HUMAN (12-156): 2.8e-65: 201: 22.15
+	Hs
		1036373 BIRC2_HUMAN (3-497): 9.73e-82: 267: 23.31		UB2J1_HUMAN (7-152): 5.57e-56: 183: 39.46
+	Hs
		919818 RSPRY_HUMAN (203-493): 4e-56: 198: 14.71		UB2D2_HUMAN (12-156): 3.65e-66: 204: 22.82
+	Hs
		895872 RSPRY_HUMAN (203-493): 4e-56: 198: 14.71		UB2D3_HUMAN (12-156): 2.8e-65: 201: 22.15
+	Hs
		849321 BIRC3_HUMAN (150-394): 2.89e-41: 158: 23.94		UB2D1_HUMAN (12-156): 3.85e-66: 204: 24.16
+	Hs
		919721 BIRC3_HUMAN (150-394): 2.89e-41: 158: 23.94		UB2D2_HUMAN (12-156): 3.65e-66: 204: 22.82
+	Hs
		895787 BIRC3_HUMAN (150-394): 2.89e-41: 158: 23.94		UB2D3_HUMAN (12-156): 2.8e-65: 201: 22.15
+	Hs
		927749 BIRC2_HUMAN (3-497): 9.73e-82: 267: 23.31		UBE2B_HUMAN (11-127): 2.6e-16: 75.5: 34.71
+	Hs
		849400 BIRC7_HUMAN (14-155): 1.47e-36: 138: 21.83		UB2D1_HUMAN (12-156): 3.85e-66: 204: 24.16
+	Hs
		895871 BIRC7_HUMAN (14-155): 1.47e-36: 138: 21.83		UB2D3_HUMAN (12-156): 2.8e-65: 201: 22.15
+	Hs
		851864 BIRC7_HUMAN (14-155): 1.47e-36: 138: 21.83		UB2E1_HUMAN (1-157): 7.51e-61: 192: 24.85