HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: MIA2 (Q96PC5)
Melanoma inhibitory activity protein 2 (MIA protein 2) (CTAGE family member 5 ER export factor) (Cutaneous T-cell lymphoma-associated antigen 5) (Meningioma-expressed antigen 6/11)
Gene: MIA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1412
+	Hs
		988378 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		EEA1_HUMAN (339-1297): 1.19e-41: 170: 8.91
+	Hs
		962131 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		TGO1_HUMAN (12-352): 2.25e-36: 153: 22.84
+	Hs
		962582 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		DAPLE_HUMAN (138-1199): 5.4e-32: 138: 9.60
+	Mm
		878608 RHOA_MOUSE (1-193): 2.21e-80: 238: 99.48		CTRO_MOUSE (310-1114): 2e-31: 136: 12.74
+	Rn
		97301 RHOA_RAT (1-193): 2.21e-80: 238: 99.48		CTRO_RAT (310-1114): 6.25e-31: 135: 13.09
+	Mm
		878598 RAC1_MOUSE (1-193): 7e-79: 235: 57.22		CTRO_MOUSE (310-1114): 2e-31: 136: 12.74
+	Hs
		587606 CDC42_HUMAN (1-193): 4.17e-76: 228: 52.33		DESP_HUMAN (184-1134): 2.44e-32: 140: 11.90
+	Mm
		878597 CDC42_MOUSE (1-193): 4.17e-76: 228: 52.33		CTRO_MOUSE (310-1114): 2e-31: 136: 12.74
+	Hs
		773156 RHOG_HUMAN (1-193): 1.49e-76: 229: 54.40		MYH10_HUMAN (91-783): 4.87e-24: 112: 8.42
+	Hs
		773143 CDC42_HUMAN (1-193): 4.17e-76: 228: 52.33		MYH10_HUMAN (91-783): 4.87e-24: 112: 8.42
+	Hs
		157168 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		CTRO_HUMAN (714-1069): 3.7e-14: 80.3: 18.54
+	Hs
		157213 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		CTRO_HUMAN (714-1069): 3.7e-14: 80.3: 18.54
+	Hs
		962225 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		KTN1_HUMAN (677-1108): 1.61e-12: 74.9: 18.44
+	Hs
		156856 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		CTRO_HUMAN (714-1069): 3.7e-14: 80.3: 18.54
+	Hs
		988492 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		KTN1_HUMAN (677-1108): 1.61e-12: 74.9: 18.44
+	Hs
		772724 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		MYH9_HUMAN (882-1300): 3.19e-12: 73.7: 10.64
+	Hs
		466334 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		KTN1_HUMAN (677-1108): 1.61e-12: 74.9: 18.44
+	Hs
		1015751 RHOG_HUMAN (1-193): 1.49e-76: 229: 54.40		UACA_HUMAN (710-1128): 4.73e-13: 76.5: 14.05
+	Hs
		1015568 RHOG_HUMAN (1-193): 1.49e-76: 229: 54.40		KTN1_HUMAN (677-1108): 1.61e-12: 74.9: 18.44
+	Hs
		772743 RHOG_HUMAN (1-193): 1.49e-76: 229: 54.40		MYH9_HUMAN (882-1300): 3.19e-12: 73.7: 10.64