HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: NGAP (Q9UJF2)
Ras GTPase-activating protein nGAP (RAS protein activator-like 2)
Gene: RASAL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RasGAP
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1139
+	Hs
		988808 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		NGAP_HUMAN (1-1139): 0: 1051: 100.00
+	Hs
		466517 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		NGAP_HUMAN (1-1139): 0: 1051: 100.00
+	Hs
		988435 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		DAB2P_HUMAN (5-1138): 0: 963: 55.74
+	Hs
		962395 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		SYGP1_HUMAN (2-1138): 0: 765: 43.10
+	Hs
		988621 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		SYGP1_HUMAN (2-1138): 0: 765: 43.10
+	Hs
		466418 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		SYGP1_HUMAN (2-1138): 0: 765: 43.10
+	Hs
		988345 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		IQGA2_HUMAN (87-757): 1.48e-150: 492: 14.63
+	Hs
		962226 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		IQGA3_HUMAN (127-711): 7.96e-135: 449: 12.44
+	Hs
		988494 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		IQGA3_HUMAN (127-711): 7.96e-135: 449: 12.44
+	Mm
		988916 RAC1_MOUSE (1-193): 7e-79: 235: 57.22		IQGA1_MOUSE (126-751): 1.61e-133: 446: 12.33
+	Hs
		466336 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		IQGA3_HUMAN (127-711): 7.96e-135: 449: 12.44
+	Hs
		862778 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		IQGA1_HUMAN (88-751): 1.82e-132: 443: 12.10
+	Hs
		862792 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		IQGA1_HUMAN (88-751): 1.82e-132: 443: 12.10
+	Hs
		466145 RHOC_HUMAN (1-193): 1.75e-77: 231: 91.71		IQGA1_HUMAN (88-751): 1.82e-132: 443: 12.10
+	Hs
		862801 RHOG_HUMAN (1-193): 1.49e-76: 229: 54.40		IQGA1_HUMAN (88-751): 1.82e-132: 443: 12.10
+	Hs
		988369 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		RASA3_HUMAN (169-570): 1.98e-123: 401: 25.97
+	Dd
		757430 RAC1A_DICDI (1-193): 1.63e-76: 229: 54.59		RGAA_DICDI (183-692): 1.32e-109: 363: 13.26
+	Dd
		144507 RAC1A_DICDI (1-193): 1.63e-76: 229: 54.59		GAPA_DICDI (214-671): 1.97e-96: 328: 13.42
+	Hs
		637875 RHOA_HUMAN (1-193): 7.2e-80: 237: 100.00		NF1_HUMAN (293-621): 8.78e-89: 317: 26.17
+	Hs
		637879 RAC1_HUMAN (1-193): 7e-79: 235: 57.22		NF1_HUMAN (293-621): 8.78e-89: 317: 26.17