HitPredict

Interactor 1: CTF4 (Q01454)
DNA polymerase alpha-binding protein (Chromosome replication protein CHL15) (Chromosome transmission fidelity protein 4) (Protein POB1)
Gene: CTF4

Interactor 2: CDC45 (Q08032)
Cell division control protein 45
Gene: CDC45

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	1.00	0.957

Property	Details
Experiments	25697176, 27397685, 31589141, 19913425, 26255844, 31765407, 37968396, 21179020
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	CDC45~Mcl1_mid
Common GO terms	GO:0000727 - double-strand break repair via break-induced replication GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006270 - DNA replication initiation GO:0031298 - replication fork protection complex and 1 others more... GO:0043596 - nuclear replication fork
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 927 Sc			1 650
+	Hs
		264152 WDHD1_HUMAN (4-924): 8.41e-166: 515: 15.49		CDC45_HUMAN (5-644): 0: 675: 24.00