HitPredict

Interactor 1: EXOSX (Q01780)
Exosome complex component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2) (P100 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (Polymyositis/scleroderma autoantigen 2)
Gene: EXOSC10

Interactor 2: EXOS1 (Q9Y3B2)
Exosome complex component CSL4 (Exosome component 1)
Gene: EXOSC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.745

The method score is based on:

Property Details
Experiments 26496610, 28514442, 24981860, 33961781, 29395067, 11812149, 21255825
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0003723 - RNA binding
GO:0005634 - nucleus
and 8 others

more...
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 885
Hs

1 195
+ Hs
+ Dm
+ Dm
+ Sp
+ Sc
+ Sc
+ Tb
+ Pf

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024