HitPredict

Interactor 1: PO5F1 (Q01860)
POU domain, class 5, transcription factor 1 (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3)
Gene: POU5F1

Interactor 2: ITCH (Q96J02)
E3 ubiquitin-protein ligase Itchy homolog (Itch) (EC 2.3.2.26) (Atrophin-1-interacting protein 4) (AIP4) (HECT-type E3 ubiquitin transferase Itchy homolog) (NFE2-associated polypeptide 1) (NAPP1)
Gene: ITCH

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.629

Property	Details
Experiments	23255053, 19997087
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 360 Hs			1 903
+	Hs
		125388 PO5F1_HUMAN (1-360): 7.32e-89: 273: 100.00		WWP2_HUMAN (1-903): 0: 816: 54.08
+	Mm
		590518 PO5F1_MOUSE (1-360): 5.33e-84: 260: 83.61		WWP2_MOUSE (1-903): 0: 820: 54.52
+	Hs
		967907 PO5F1_HUMAN (1-360): 7.32e-89: 273: 100.00		HUWE1_HUMAN (415-902): 1.81e-160: 523: 34.88
+	Mm
		590261 PO5F1_MOUSE (1-360): 5.33e-84: 260: 83.61		NEDD4_MOUSE (13-426): 2.27e-52: 199: 18.38