HitPredict

Interactor 1: E9PMD8 (E9PMD8)
Proteasome 26S subunit, ATPase 3
Gene: PSMC3

Interactor 2: PSA4 (P25789)
Proteasome subunit alpha type-4 (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome component C9) (Proteasome subunit L) (Proteasome subunit alpha-3) (alpha-3)
Gene: PSMA4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA~Proteasome_A_N
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 301 Hs			1 261
+	Hs
		114579 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		H0YKT8_HUMAN (25-205): 1.08e-132: 374: 100.00
+	Hs
		114587 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		H0YKT8_HUMAN (25-205): 1.08e-132: 374: 100.00
+	Dm
		611471 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSA4_DROME (1-242): 1.03e-92: 275: 72.25
+	Dm
		874988 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSA5_DROME (3-241): 7.27e-89: 265: 32.11
+	Hs
		610230 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA4_HUMAN (1-237): 2.21e-98: 290: 100.00
+	Dm
		875057 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSA6_DROME (2-244): 1.15e-86: 259: 29.10
+	Hs
		97073 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA6_HUMAN (2-244): 3.53e-92: 273: 31.84
+	Hs
		681583 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA4_HUMAN (1-237): 2.21e-98: 290: 100.00
+	Hs
		610283 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA6_HUMAN (2-244): 3.53e-92: 273: 31.84
+	Hs
		97059 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA1_HUMAN (4-259): 2.98e-87: 261: 28.57
+	Hs
		165253 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA7_HUMAN (5-238): 3.1e-91: 271: 33.19
+	Hs
		610227 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA1_HUMAN (4-259): 2.98e-87: 261: 28.57
+	Hs
		778646 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA6_HUMAN (2-244): 3.53e-92: 273: 31.84
+	Hs
		165277 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA7_HUMAN (5-238): 3.1e-91: 271: 33.19
+	Hs
		680794 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA1_HUMAN (4-259): 2.98e-87: 261: 28.57
+	Dm
		821820 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSA2_DROME (2-221): 4.77e-44: 150: 39.64
+	Sp
		785694 PRS4_SCHPO (51-301): 6.16e-85: 263: 38.04		PSA4_SCHPO (5-251): 2.18e-40: 141: 34.54
+	Hs
		97060 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA2_HUMAN (3-214): 6.07e-42: 145: 38.68
+	Hs
		610228 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA2_HUMAN (3-214): 6.07e-42: 145: 38.68
+	Hs
		681115 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA2_HUMAN (3-214): 6.07e-42: 145: 38.68