HitPredict

Interactor 1: E9PMD8 (E9PMD8)
Proteasome 26S subunit, ATPase 3
Gene: PSMC3

Interactor 2: PSA2 (P25787)
Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3) (Proteasome subunit alpha-2) (alpha-2)
Gene: PSMA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA~Proteasome_A_N
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 301 Hs			1 234
+	Dm
		874988 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSA5_DROME (1-234): 9.16e-98: 286: 33.88
+	Dm
		821820 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSA2_DROME (1-233): 1.23e-93: 275: 78.11
+	Hs
		97063 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA5_HUMAN (1-233): 9.54e-98: 286: 30.96
+	Ce
		303807 PRS6A_CAEEL (20-301): 6.72e-70: 224: 75.89		PSA2_CAEEL (6-233): 3.36e-107: 310: 65.22
+	Hs
		610228 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA2_HUMAN (1-234): 1e-97: 286: 100.00
+	Hs
		610234 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA5_HUMAN (1-233): 9.54e-98: 286: 30.96
+	Hs
		97073 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA6_HUMAN (2-234): 8.26e-91: 269: 34.73
+	Hs
		97059 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA1_HUMAN (1-233): 5.15e-90: 267: 30.67
+	Hs
		681115 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA2_HUMAN (1-234): 1e-97: 286: 100.00
+	Hs
		700565 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA5_HUMAN (1-233): 9.54e-98: 286: 30.96
+	Hs
		610283 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA6_HUMAN (2-234): 8.26e-91: 269: 34.73
+	Hs
		610227 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA1_HUMAN (1-233): 5.15e-90: 267: 30.67
+	Hs
		165253 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA7_HUMAN (6-231): 5.97e-90: 266: 36.52
+	Hs
		778646 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA6_HUMAN (2-234): 8.26e-91: 269: 34.73
+	Hs
		680794 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA1_HUMAN (1-233): 5.15e-90: 267: 30.67
+	Hs
		165277 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA7_HUMAN (6-231): 5.97e-90: 266: 36.52
+	Sp
		785694 PRS4_SCHPO (51-301): 6.16e-85: 263: 38.04		PSA4_SCHPO (5-212): 2.24e-45: 153: 38.10
+	Hs
		97062 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA4_HUMAN (4-211): 1.25e-42: 146: 38.68
+	Hs
		610230 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA4_HUMAN (4-211): 1.25e-42: 146: 38.68
+	Hs
		681583 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA4_HUMAN (4-211): 1.25e-42: 146: 38.68