HitPredict

Interactor 1: E9PMD8 (E9PMD8)
Proteasome 26S subunit, ATPase 3
Gene: PSMC3

Interactor 2: PSA1 (P25786)
Proteasome subunit alpha type-1 (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain) (Proteasome subunit alpha-6) (alpha-6)
Gene: PSMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA~Proteasome_A_N
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 301 Hs			1 263
+	Dm
		875021 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		Q9VK14_DROME (1-263): 2.77e-100: 295: 49.81
+	Dm
		556649 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSA1_DROME (1-260): 3.17e-99: 292: 52.42
+	Hs
		610227 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA1_HUMAN (1-263): 2.81e-109: 317: 100.00
+	Dm
		874988 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSA5_DROME (1-237): 3.38e-92: 273: 28.86
+	Hs
		680794 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA1_HUMAN (1-263): 2.81e-109: 317: 100.00
+	Hs
		97063 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA5_HUMAN (1-236): 4.19e-93: 275: 28.81
+	Hs
		97073 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA6_HUMAN (1-240): 7.5e-93: 275: 25.00
+	Hs
		165253 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA7_HUMAN (6-234): 5.38e-96: 283: 33.19
+	Hs
		97062 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA4_HUMAN (1-233): 2.18e-91: 272: 28.75
+	Dm
		556722 Q9V3V6_DROME (34-301): 1.28e-69: 223: 85.82		PSA1_DROME (1-260): 3.17e-99: 292: 52.42
+	Hs
		610234 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA5_HUMAN (1-236): 4.19e-93: 275: 28.81
+	Hs
		610283 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA6_HUMAN (1-240): 7.5e-93: 275: 25.00
+	Hs
		610230 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA4_HUMAN (1-233): 2.18e-91: 272: 28.75
+	Hs
		165277 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA7_HUMAN (6-234): 5.38e-96: 283: 33.19
+	Hs
		700565 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA5_HUMAN (1-236): 4.19e-93: 275: 28.81
+	Hs
		778646 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA6_HUMAN (1-240): 7.5e-93: 275: 25.00
+	Hs
		681583 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA4_HUMAN (1-233): 2.18e-91: 272: 28.75
+	Dm
		1376921 Q9V3V6_DROME (34-301): 1.28e-69: 223: 85.82		PSA5_DROME (1-237): 3.38e-92: 273: 28.86
+	Dm
		652730 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSA71_DROME (4-233): 2.41e-38: 136: 33.48
+	Dm
		652767 Q9V3V6_DROME (34-301): 1.28e-69: 223: 85.82		PSA71_DROME (4-233): 2.41e-38: 136: 33.48