Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE
Interactor 2: MP2K1 (Q02750)
Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)
Gene: MAP2K1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.79 | 0.60 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35271311, 31980649, 17979178, unassigned2173 |
| Identification Methods | affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000165 - MAPK cascade GO:0005634 - nucleus GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol GO:0005925 - focal adhesion and 2 others more... |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
