HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: MYO9B (Q13459)
Unconventional myosin-IXb (Unconventional myosin-9b)
Gene: MYO9B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RA~Ras, Ras~RhoGAP
Common GO terms	GO:0005829 - cytosol GO:0007266 - Rho protein signal transduction
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 2157
+	Hs
		962018 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		MYO9B_HUMAN (1-2157): 0: 1573: 100.00
+	Hs
		466239 RHOC_HUMAN (1-196): 8.71e-76: 227: 83.16		MYO9B_HUMAN (1-2157): 0: 1573: 100.00
+	Hs
		955132 CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49		MYO9B_HUMAN (1-2157): 0: 1573: 100.00
+	Hs
		988821 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		MYO5B_HUMAN (67-1775): 0: 925: 19.70
+	Hs
		601517 RHOQ_HUMAN (2-195): 6.74e-68: 207: 51.74		MYO5A_HUMAN (64-1775): 0: 933: 19.94
+	Hs
		126892 RHOD_HUMAN (7-182): 3.38e-66: 203: 53.98		MYO5A_HUMAN (64-1775): 0: 933: 19.94
+	Ce
		98436 RHO1_CAEEL (1-196): 4.79e-75: 225: 78.57		F0IWT2_CAEEL (1091-2040): 8.81e-99: 357: 20.33
+	Hs
		74012 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		MYO9A_HUMAN (591-2140): 3.81e-84: 311: 19.84
+	Hs
		74018 RHOB_HUMAN (1-196): 8.92e-78: 232: 100.00		MYO9A_HUMAN (591-2140): 3.81e-84: 311: 19.84
+	Hs
		74011 CDC42_HUMAN (1-196): 7.26e-75: 225: 49.49		MYO9A_HUMAN (591-2140): 3.81e-84: 311: 19.84
+	Hs
		953688 RAC3_HUMAN (1-179): 5.41e-75: 225: 57.54		MYO10_HUMAN (792-1023): 2.22e-34: 147: 35.44
+	Hs
		772724 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		MYH9_HUMAN (947-1478): 1.78e-13: 78.7: 11.50
+	Hs
		772743 RHOG_HUMAN (1-196): 3.36e-76: 228: 51.53		MYH9_HUMAN (947-1478): 1.78e-13: 78.7: 11.50