HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: TCOF (Q13428)
Treacle protein (Treacher Collins syndrome protein)
Gene: TCOF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30804502, 34349018
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0046982 - protein heterodimerization activity
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 1488
+	Hs
		979834 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		NIPBL_HUMAN (453-1488): 5.28e-59: 227: 10.70
+	Hs
		979655 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		MDC1_HUMAN (59-1388): 1.46e-46: 186: 10.51
+	Hs
		979859 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		ANR11_HUMAN (176-1080): 1.73e-30: 134: 10.59
+	Hs
		979778 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		BCORL_HUMAN (78-1472): 1.09e-15: 85.3: 10.49
+	Hs
		979658 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		NCOA6_HUMAN (370-1466): 6.08e-15: 83.1: 7.27
+	Hs
		980061 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		TITIN_HUMAN (487-1460): 1.21e-13: 78.9: 9.00
+	Hs
		161444 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		KMT2D_HUMAN (21-1171): 1.03e-11: 72.6: 10.19
+	Hs
		980189 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		MINT_HUMAN (22-675): 3.29e-11: 70.8: 9.96
+	Hs
		979867 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		SRCAP_HUMAN (103-719): 5.25e-10: 66.7: 17.09
+	Hs
		979515 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		ANK2_HUMAN (195-1161): 9.85e-10: 65.9: 15.17
+	Hs
		979957 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		MILK2_HUMAN (420-909): 2.22e-09: 64.4: 19.48