Interactor 1: ACVR1 (Q04771)
Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)
Gene: ACVR1

Interactor 2: TGFA1 (Q8WUH2)
Transforming growth factor-beta receptor-associated protein 1 (TGF-beta receptor-associated protein 1) (TRAP-1) (TRAP1)
Gene: TGFBRAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.667

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0046332 - SMAD binding
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 509
Hs

1 860
+ Hs
+ Hs
+ Hs
+ At
+ Zm

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Last updated: 15 Jul 2024