HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: STF1 (Q13285)
Steroidogenic factor 1 (SF-1) (STF-1) (hSF-1) (Adrenal 4-binding protein) (Fushi tarazu factor homolog 1) (Nuclear receptor subfamily 5 group A member 1) (Steroid hormone receptor Ad4BP)
Gene: NR5A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 461
+	Hs
		593985 NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14		STF1_HUMAN (1-461): 1.7e-126: 376: 100.00
+	Hs
		362275 ABL1_HUMAN (4-139): 4.41e-22: 95.5: 35.46		STF1_HUMAN (1-461): 1.7e-126: 376: 100.00
+	Hs
		440536 FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58		STF1_HUMAN (1-461): 1.7e-126: 376: 100.00
+	Hs
		1101133 ITSN1_HUMAN (122-216): 3.21e-11: 64.2: 23.53		STF1_HUMAN (1-461): 1.7e-126: 376: 100.00
+	Hs
		557279 SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58		STF1_HUMAN (1-461): 1.7e-126: 376: 100.00
+	Hs
		879553 ITSN2_HUMAN (108-216): 6.53e-13: 69.2: 18.92		NR2C2_HUMAN (11-457): 1.95e-116: 355: 21.80
+	Hs
		463404 LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47		NR2C2_HUMAN (11-457): 1.95e-116: 355: 21.80
+	Hs
		343252 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		ERR2_HUMAN (2-166): 2.55e-54: 189: 40.72
+	Hs
		440104 LCK_HUMAN (3-202): 7.98e-34: 128: 28.44		Q58EY0_HUMAN (12-457): 5.43e-85: 270: 20.56
+	Hs
		440164 LCK_HUMAN (3-202): 7.98e-34: 128: 28.44		RORB_HUMAN (12-457): 7.05e-85: 270: 20.56
+	Mm
		362437 ABL1_MOUSE (4-139): 4.08e-22: 95.9: 35.46		PPARG_MOUSE (2-457): 3.23e-76: 248: 19.00
+	Hs
		543451 SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58		VDR_HUMAN (5-456): 1.74e-83: 265: 17.11
+	Hs
		557182 SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58		RORG_HUMAN (12-459): 1.58e-79: 257: 20.73
+	Hs
		282918 FGR_HUMAN (98-215): 3.91e-12: 66.6: 20.00		NR1I2_HUMAN (10-456): 7.9e-76: 245: 20.09
+	Hs
		557079 SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58		RXRA_HUMAN (12-143): 5.5e-47: 170: 38.41
+	Hs
		397094 ITSN2_HUMAN (108-216): 6.53e-13: 69.2: 18.92		ESR1_HUMAN (13-154): 2.15e-39: 151: 34.90
+	Hs
		397189 VAV3_HUMAN (3-57): 2.47e-12: 67.1: 38.18		ESR1_HUMAN (13-154): 2.15e-39: 151: 34.90
+	Hs
		395341 YES_HUMAN (71-215): 7.5e-12: 65.8: 16.33		ESR1_HUMAN (13-154): 2.15e-39: 151: 34.90
+	Hs
		395400 SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58		ESR1_HUMAN (13-154): 2.15e-39: 151: 34.90