HitPredict

Interactor 1: RING1 (Q06587)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)
Gene: RING1

Interactor 2: MGAP (Q8IWI9)
MAX gene-associated protein (MAX dimerization protein 5)
Gene: MGA

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	27705803, 24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 3065
+	Hs
		1218708 RING2_HUMAN (8-406): 4.9e-100: 302: 54.25		MGAP_HUMAN (1-3065): 0: 5622: 100.00
+	Hs
		717992 BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16		MGAP_HUMAN (1-3065): 0: 5622: 100.00
+	Hs
		718407 PCGF2_HUMAN (31-377): 1.44e-41: 151: 14.37		MGAP_HUMAN (1-3065): 0: 5622: 100.00
+	Hs
		1218718 PCGF6_HUMAN (31-157): 1.02e-40: 149: 23.08		MGAP_HUMAN (1-3065): 0: 5622: 100.00
+	Hs
		1218715 PCGF1_HUMAN (25-133): 3.54e-40: 145: 25.00		MGAP_HUMAN (1-3065): 0: 5622: 100.00
+	Hs
		1108514 PCGF3_HUMAN (34-224): 6.2e-39: 141: 17.53		MGAP_HUMAN (1-3065): 0: 5622: 100.00
+	Hs
		1197567 PCGF5_HUMAN (31-147): 4.96e-38: 139: 23.33		MGAP_HUMAN (1-3065): 0: 5622: 100.00
+	Mm
		57636 RING2_MOUSE (8-406): 2.94e-100: 303: 54.25		MGAP_MOUSE (1-3065): 0: 5191: 80.91
+	Hs
		171020 RING1_HUMAN (1-406): 2.01e-114: 342: 100.00		TBXT_HUMAN (50-331): 1.62e-103: 342: 35.79
+	Hs
		1304062 RING2_HUMAN (8-406): 4.9e-100: 302: 54.25		TBX5_HUMAN (9-305): 7.22e-103: 343: 38.93
+	Hs
		1246154 COP1_HUMAN (40-326): 3.5e-39: 151: 18.31		TBX5_HUMAN (9-305): 7.22e-103: 343: 38.93
+	Hs
		171072 PCGF1_HUMAN (25-133): 3.54e-40: 145: 25.00		TBXT_HUMAN (50-331): 1.62e-103: 342: 35.79
+	Hs
		1085179 PCGF1_HUMAN (25-133): 3.54e-40: 145: 25.00		TBR1_HUMAN (39-299): 2.36e-93: 321: 37.18