HitPredict

Interactor 1: F1M4A0 (F1M4A0)
Tight junction protein 1
Gene: Tjp1

Interactor 2: FAK1 (O35346)
Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)
Gene: Ptk2

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19470647
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1725 Rn			1 1055
+	Hs
		400706 ZO1_HUMAN (6-1725): 0: 749: 90.48		RAF1_HUMAN (168-702): 7.2e-128: 405: 18.89
+	Hs
		710528 PALS2_HUMAN (358-781): 1.11e-90: 307: 15.76		EPHA2_HUMAN (379-763): 6.45e-117: 385: 32.57
+	Hs
		463806 PALS2_HUMAN (358-781): 1.11e-90: 307: 15.76		LYN_HUMAN (287-691): 6.62e-122: 384: 30.15
+	Hs
		168609 CSKP_HUMAN (216-783): 1.54e-75: 274: 14.89		RAF1_HUMAN (168-702): 7.2e-128: 405: 18.89
+	Rn
		76720 PALS1_RAT (263-783): 7.39e-77: 272: 16.06		SRC_RAT (287-689): 1.31e-128: 403: 29.56
+	Hs
		168616 CSKP_HUMAN (216-783): 1.54e-75: 274: 14.89		HCK_HUMAN (287-691): 3.72e-127: 399: 29.24
+	Hs
		440107 MPP7_HUMAN (270-783): 7.38e-77: 269: 14.85		LCK_HUMAN (293-691): 2.17e-127: 399: 29.00
+	Hs
		557298 MPP2_HUMAN (339-783): 2.59e-73: 258: 15.97		SRC_HUMAN (287-689): 5.99e-129: 404: 29.80
+	Hs
		168659 CSKP_HUMAN (216-783): 1.54e-75: 274: 14.89		EPHA4_HUMAN (378-756): 1.97e-117: 387: 34.29
+	Hs
		168639 CSKP_HUMAN (216-783): 1.54e-75: 274: 14.89		EPHA2_HUMAN (379-763): 6.45e-117: 385: 32.57
+	Hs
		168615 CSKP_HUMAN (216-783): 1.54e-75: 274: 14.89		LYN_HUMAN (287-691): 6.62e-122: 384: 30.15
+	Hs
		710288 MPP7_HUMAN (270-783): 7.38e-77: 269: 14.85		EPHA2_HUMAN (379-763): 6.45e-117: 385: 32.57
+	Hs
		168694 CSKP_HUMAN (216-783): 1.54e-75: 274: 14.89		EPHA7_HUMAN (388-757): 2.79e-114: 379: 32.44
+	Hs
		463569 MPP7_HUMAN (270-783): 7.38e-77: 269: 14.85		LYN_HUMAN (287-691): 6.62e-122: 384: 30.15
+	Hs
		1147344 MPP7_HUMAN (270-783): 7.38e-77: 269: 14.85		EPHA7_HUMAN (388-757): 2.79e-114: 379: 32.44
+	Hs
		710361 PALS1_HUMAN (263-783): 6.11e-74: 263: 15.88		EPHA2_HUMAN (379-763): 6.45e-117: 385: 32.57
+	Hs
		168622 CSKP_HUMAN (216-783): 1.54e-75: 274: 14.89		FGFR1_HUMAN (360-729): 2.16e-112: 369: 29.37
+	Hs
		541539 MPP7_HUMAN (270-783): 7.38e-77: 269: 14.85		FGFR1_HUMAN (360-729): 2.16e-112: 369: 29.37
+	Hs
		440486 DLG4_HUMAN (4-92): 1.84e-25: 116: 32.97		FYN_HUMAN (287-689): 3.36e-130: 407: 28.61
+	Rn
		723904 DLG4_RAT (4-92): 1.35e-25: 117: 32.97		SRC_RAT (287-689): 1.31e-128: 403: 29.56