HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: LUC7L (Q9NQ29)
Putative RNA-binding protein Luc7-like 1 (Putative SR protein LUC7B1) (SR+89)
Gene: LUC7L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.669

Property	Details
Experiments	33961781, 28514442, 34133714
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding GO:0006376 - mRNA splice site recognition
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 371
+	Hs
		1029116 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		LUC7L_HUMAN (1-371): 3.08e-112: 333: 100.00
+	Hs
		1029169 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		LC7L2_HUMAN (1-264): 6.79e-82: 256: 84.47
+	Hs
		1084423 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		LUC7L_HUMAN (1-371): 3.08e-112: 333: 100.00
+	Hs
		993004 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		LC7L2_HUMAN (1-264): 6.79e-82: 256: 84.47
+	Hs
		1329991 PABP3_HUMAN (8-203): 1.09e-33: 129: 16.18		LC7L2_HUMAN (1-264): 6.79e-82: 256: 84.47
+	Hs
		308193 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		LC7L3_HUMAN (8-244): 4.22e-62: 206: 33.75
+	Hs
		1084460 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		LC7L2_HUMAN (1-264): 6.79e-82: 256: 84.47
+	Hs
		1031502 PABP4_HUMAN (118-200): 2.19e-13: 71.2: 16.67		LC7L2_HUMAN (1-264): 6.79e-82: 256: 84.47
+	Sc
		376945 PABP_YEAST (123-203): 2.42e-12: 68.1: 22.73		LUC7_YEAST (5-248): 8.53e-71: 223: 32.54
+	Dm
		970879 RBP1_DROME (16-88): 9.45e-29: 107: 49.32		Q9W3X8_DROME (165-272): 2.25e-21: 96.7: 24.56