HitPredict

Interactor 1: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Interactor 2: HOMEZ (Q8IX15)
Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper-containing factor)
Gene: HOMEZ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	25416956, 32296183
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 197 Hs			1 550
+	Hs
		620144 TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59		PAX7_HUMAN (164-465): 1.06e-57: 202: 11.96
+	Hs
		620142 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		PAX7_HUMAN (164-465): 1.06e-57: 202: 11.96
+	Hs
		620143 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		PAX7_HUMAN (164-465): 1.06e-57: 202: 11.96
+	Mm
		623700 TLE4_MOUSE (2-191): 3.77e-112: 338: 68.59		PAX3_MOUSE (163-465): 3.94e-50: 181: 11.59
+	Hs
		839732 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		LHX2_HUMAN (201-467): 4.95e-47: 171: 10.29
+	Hs
		620146 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		PAX7_HUMAN (164-465): 1.06e-57: 202: 11.96
+	Hs
		980622 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		LHX8_HUMAN (127-474): 6.17e-39: 147: 12.26
+	Hs
		980912 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		LHX6_HUMAN (152-430): 1.14e-44: 163: 12.59
+	Hs
		641379 TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59		PAX6_HUMAN (193-494): 4.6e-37: 144: 10.60
+	Hs
		641377 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		PAX6_HUMAN (193-494): 4.6e-37: 144: 10.60
+	Hs
		641378 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		PAX6_HUMAN (193-494): 4.6e-37: 144: 10.60
+	Hs
		839735 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		LHX2_HUMAN (201-467): 4.95e-47: 171: 10.29
+	Hs
		641385 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		PAX6_HUMAN (193-494): 4.6e-37: 144: 10.60
+	Hs
		980956 TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59		VSX1_HUMAN (282-418): 2.41e-12: 70.4: 17.14
+	Hs
		980659 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		VSX1_HUMAN (282-418): 2.41e-12: 70.4: 17.14
+	Hs
		980760 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		ZFHX3_HUMAN (65-432): 2.69e-15: 81.6: 14.10
+	Hs
		980893 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		VSX1_HUMAN (282-418): 2.41e-12: 70.4: 17.14
+	Hs
		993437 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		ZFHX3_HUMAN (65-432): 2.69e-15: 81.6: 14.10
+	Hs
		993632 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		VSX1_HUMAN (282-418): 2.41e-12: 70.4: 17.14
+	Ce
		105784 UNC37_CAEEL (18-160): 8.43e-43: 153: 28.47		PAX3H_CAEEL (192-466): 6.4e-33: 129: 13.89