HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: SF3A2 (Q15428)
Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62)
Gene: SF3A2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17332742
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~zf-met
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing and 1 others more... GO:0016607 - nuclear speck
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 464
+	Hs
		992787 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		SF3A2_HUMAN (1-464): 5.79e-72: 236: 100.00
+	Hs
		1028927 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		SF3A2_HUMAN (1-464): 5.79e-72: 236: 100.00
+	Hs
		1028554 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		SF3A2_HUMAN (1-464): 5.79e-72: 236: 100.00
+	Hs
		1028665 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		SF3A2_HUMAN (1-464): 5.79e-72: 236: 100.00
+	Hs
		1029092 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		ZN768_HUMAN (277-449): 2.74e-22: 101: 27.32
+	Hs
		993831 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		ZN768_HUMAN (277-449): 2.74e-22: 101: 27.32
+	Hs
		1028819 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		ZN768_HUMAN (277-449): 2.74e-22: 101: 27.32
+	Hs
		516595 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		KMT2C_HUMAN (73-462): 1.38e-16: 85.1: 12.59
+	Hs
		516609 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		TITIN_HUMAN (290-460): 7.67e-09: 60.4: 18.50
+	Hs
		1031405 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		TITIN_HUMAN (290-460): 7.67e-09: 60.4: 18.50