HitPredict

Interactor 1: ULS1 (Q08562)
ATP-dependent helicase ULS1 (EC 3.6.4.-) (Role in silencing protein 1) (Ubiquitin ligase for SUMO conjugates protein 1)
Gene: ULS1

Interactor 2: SMT3 (Q12306)
Ubiquitin-like protein SMT3
Gene: SMT3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.690

Property	Details
Experiments	11283351, 23122649, 17728242, 15590687
Identification Methods	two hybrid pooling approach, unspecified method, pull down, two hybrid, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1619 Sc			1 101
+	Sp
		140817 YF2C_SCHPO (888-1618): 6.01e-163: 519: 30.38		PMT3_SCHPO (4-101): 2.02e-37: 123: 53.00
+	Hs
		902820 ARIP4_HUMAN (755-1614): 8.59e-148: 493: 17.42		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		879164 ARIP4_HUMAN (755-1614): 8.59e-148: 493: 17.42		SUMO3_HUMAN (9-98): 2.24e-34: 115: 43.96
+	Sp
		140852 YG42_SCHPO (842-1618): 2.39e-148: 484: 33.04		PMT3_SCHPO (4-101): 2.02e-37: 123: 53.00
+	Hs
		928235 ARIP4_HUMAN (755-1614): 8.59e-148: 493: 17.42		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Hs
		802413 ATRX_HUMAN (65-1617): 5.14e-124: 434: 14.65		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Ce
		879058 Q18241_CAEEL (756-1618): 2.08e-126: 429: 17.15		SUMO_CAEEL (12-98): 3.17e-32: 109: 39.77
+	Hs
		902554 CHD3_HUMAN (1281-1619): 1.32e-73: 274: 17.84		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		928081 CHD3_HUMAN (1281-1619): 1.32e-73: 274: 17.84		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Hs
		902761 CHD8_HUMAN (1281-1614): 4.02e-65: 247: 17.01		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		879157 CHD8_HUMAN (1281-1614): 4.02e-65: 247: 17.01		SUMO3_HUMAN (9-98): 2.24e-34: 115: 43.96
+	Hs
		928205 CHD8_HUMAN (1281-1614): 4.02e-65: 247: 17.01		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Hs
		1241448 CHD8_HUMAN (1281-1614): 4.02e-65: 247: 17.01		NF2IP_HUMAN (10-91): 4.5e-27: 104: 21.95
+	Hs
		658709 SMCA1_HUMAN (1432-1611): 2.13e-66: 247: 26.15		NF2IP_HUMAN (10-91): 4.5e-27: 104: 21.95
+	Hs
		846913 SMCA4_HUMAN (1286-1608): 4.51e-60: 230: 20.62		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		902642 SRCAP_HUMAN (1463-1597): 2.44e-17: 91.3: 34.07		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		1170070 SRCAP_HUMAN (1463-1597): 2.44e-17: 91.3: 34.07		NF2IP_HUMAN (10-91): 4.5e-27: 104: 21.95