HitPredict

Interactor 1: TBA4A (P68366)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)
Gene: TUBA4A

Interactor 2: SH2D3 (Q8N5H7)
SH2 domain-containing protein 3C (Cas/HEF1-associated signal transducer) (Chat-H) (Novel SH2-containing protein 3) (SH2 domain-containing Eph receptor-binding protein 1) (SHEP1)
Gene: SH2D3C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 448 Hs			1 860
+	Hs
		1259458 TBA1A_HUMAN (1-439): 0: 712: 97.04		SH23A_HUMAN (207-853): 3.11e-177: 525: 33.03
+	Hs
		557213 TBA4A_HUMAN (1-448): 0: 723: 100.00		SRC_HUMAN (20-392): 2.1e-60: 216: 12.79
+	Hs
		557212 TBA1B_HUMAN (1-439): 0: 714: 97.49		SRC_HUMAN (20-392): 2.1e-60: 216: 12.79
+	Hs
		996917 TBA4A_HUMAN (1-448): 0: 723: 100.00		BTK_HUMAN (24-426): 8.87e-52: 194: 10.94
+	Hs
		855742 TBA1C_HUMAN (1-448): 0: 725: 96.21		CRK_HUMAN (213-480): 7.42e-53: 188: 17.75
+	Hs
		457199 TBB5_HUMAN (1-439): 0: 696: 40.55		SRC_HUMAN (20-392): 2.1e-60: 216: 12.79
+	Mm
		997222 TBA4A_MOUSE (1-448): 0: 723: 100.00		SHC1_MOUSE (95-323): 1.18e-50: 189: 23.28
+	Hs
		463606 TBA1A_HUMAN (1-439): 0: 712: 97.04		LYN_HUMAN (127-400): 2.38e-54: 198: 11.60
+	Hs
		855662 TBA1A_HUMAN (1-439): 0: 712: 97.04		CRK_HUMAN (213-480): 7.42e-53: 188: 17.75
+	Hs
		457317 TBB5_HUMAN (1-439): 0: 696: 40.55		BLK_HUMAN (100-397): 7.63e-55: 199: 13.29
+	Hs
		711404 TBA1C_HUMAN (1-448): 0: 725: 96.21		SHC1_HUMAN (97-322): 5.56e-44: 170: 24.02
+	Hs
		439902 TBB5_HUMAN (1-439): 0: 696: 40.55		LCK_HUMAN (123-424): 9.16e-53: 194: 10.59
+	Hs
		457295 TBB5_HUMAN (1-439): 0: 696: 40.55		CRK_HUMAN (213-480): 7.42e-53: 188: 17.75
+	Hs
		711302 TBA1B_HUMAN (1-439): 0: 714: 97.49		SHC1_HUMAN (97-322): 5.56e-44: 170: 24.02
+	Hs
		711372 TBA1A_HUMAN (1-439): 0: 712: 97.04		SHC1_HUMAN (97-322): 5.56e-44: 170: 24.02
+	Hs
		457249 TBB5_HUMAN (1-439): 0: 696: 40.55		SHC1_HUMAN (97-322): 5.56e-44: 170: 24.02
+	Hs
		987902 TBA1C_HUMAN (1-448): 0: 725: 96.21		GRB2_HUMAN (214-310): 1.18e-27: 113: 27.00
+	Hs
		987525 TBA4A_HUMAN (1-448): 0: 723: 100.00		GRB2_HUMAN (214-310): 1.18e-27: 113: 27.00
+	Hs
		987524 TBA1B_HUMAN (1-439): 0: 714: 97.49		GRB2_HUMAN (214-310): 1.18e-27: 113: 27.00
+	Hs
		699692 TBA1B_HUMAN (1-439): 0: 714: 97.49		P85A_HUMAN (193-323): 4.95e-18: 91.2: 21.17