HitPredict

Interactor 1: TBA4A (P68368)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 4) (Alpha-tubulin isotype M-alpha-4) (Tubulin alpha-4 chain)
Gene: Tuba4a

Interactor 2: SHC1 (P98083)
SHC-transforming protein 1 (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	20697350
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 448 Mm			1 579
+	Hs
		711404 TBA1C_HUMAN (1-448): 0: 725: 96.21		SHC1_HUMAN (1-579): 4.12e-180: 522: 94.51
+	Hs
		711302 TBA1B_HUMAN (1-439): 0: 714: 97.49		SHC1_HUMAN (1-579): 4.12e-180: 522: 94.51
+	Hs
		711372 TBA1A_HUMAN (1-439): 0: 712: 97.04		SHC1_HUMAN (1-579): 4.12e-180: 522: 94.51
+	Hs
		457249 TBB5_HUMAN (1-439): 0: 696: 40.55		SHC1_HUMAN (1-579): 4.12e-180: 522: 94.51
+	Hs
		557213 TBA4A_HUMAN (1-448): 0: 723: 100.00		SRC_HUMAN (334-570): 2.53e-44: 167: 16.87
+	Mm
		59666 TBA1A_MOUSE (1-439): 0: 712: 97.04		A2AM67_MOUSE (191-571): 6.38e-47: 172: 15.44
+	Hs
		997033 TBA4A_HUMAN (1-448): 0: 723: 100.00		SH2D3_HUMAN (333-578): 1.81e-40: 159: 22.75
+	Mm
		1023478 TBB5_MOUSE (1-439): 0: 696: 40.55		ANS1B_MOUSE (39-364): 4.31e-49: 185: 17.96
+	Hs
		557212 TBA1B_HUMAN (1-439): 0: 714: 97.49		SRC_HUMAN (334-570): 2.53e-44: 167: 16.87
+	Hs
		594031 TBA1A_HUMAN (1-439): 0: 712: 97.04		NCK1_HUMAN (360-571): 2.07e-42: 158: 19.01
+	Hs
		457199 TBB5_HUMAN (1-439): 0: 696: 40.55		SRC_HUMAN (334-570): 2.53e-44: 167: 16.87
+	Hs
		457317 TBB5_HUMAN (1-439): 0: 696: 40.55		BLK_HUMAN (362-577): 2.02e-40: 155: 18.14
+	Hs
		136425 TBA1C_HUMAN (1-448): 0: 725: 96.21		P85B_HUMAN (478-575): 1.08e-18: 91.9: 23.53
+	Hs
		699692 TBA1B_HUMAN (1-439): 0: 714: 97.49		P85A_HUMAN (478-575): 3.93e-19: 93.5: 24.51
+	Hs
		987902 TBA1C_HUMAN (1-448): 0: 725: 96.21		GRB2_HUMAN (478-574): 1.34e-15: 77.9: 30.48
+	Hs
		987525 TBA4A_HUMAN (1-448): 0: 723: 100.00		GRB2_HUMAN (478-574): 1.34e-15: 77.9: 30.48
+	Hs
		1259458 TBA1A_HUMAN (1-439): 0: 712: 97.04		SH23A_HUMAN (471-577): 4.04e-17: 86.8: 33.06
+	Hs
		987524 TBA1B_HUMAN (1-439): 0: 714: 97.49		GRB2_HUMAN (478-574): 1.34e-15: 77.9: 30.48
+	Hs
		136257 TBB5_HUMAN (1-439): 0: 696: 40.55		P85B_HUMAN (478-575): 1.08e-18: 91.9: 23.53
+	Hs
		457357 TBB5_HUMAN (1-439): 0: 696: 40.55		GRB2_HUMAN (478-574): 1.34e-15: 77.9: 30.48