HitPredict

Interactor 1: SHC1 (P29353)
SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 583 Hs			1 449
+	Mm
		997222 SHC1_MOUSE (1-583): 1.06e-180: 524: 94.51		TBA4A_MOUSE (1-448): 0: 724: 96.21
+	Hs
		711302 SHC1_HUMAN (1-583): 0: 529: 100.00		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		711372 SHC1_HUMAN (1-583): 0: 529: 100.00		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		457249 SHC1_HUMAN (1-583): 0: 529: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		711425 SHC1_HUMAN (1-583): 0: 529: 100.00		TBA8_HUMAN (1-439): 0: 698: 90.66
+	Hs
		711303 SHC1_HUMAN (1-583): 0: 529: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		711407 SHC1_HUMAN (1-583): 0: 529: 100.00		TBB2B_HUMAN (1-440): 0: 697: 40.23
+	Hs
		584513 VAV_HUMAN (154-578): 2.52e-55: 202: 11.97		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		584562 VAV_HUMAN (154-578): 2.52e-55: 202: 11.97		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		584558 VAV_HUMAN (154-578): 2.52e-55: 202: 11.97		TBA3E_HUMAN (1-439): 0: 700: 96.13
+	Hs
		457209 VAV_HUMAN (154-578): 2.52e-55: 202: 11.97		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		584514 VAV_HUMAN (154-578): 2.52e-55: 202: 11.97		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Mm
		1023478 ANS1B_MOUSE (39-361): 8.03e-51: 191: 19.41		TBB5_MOUSE (1-439): 0: 699: 41.00
+	Mm
		997598 ANS1B_MOUSE (39-361): 8.03e-51: 191: 19.41		TBB4B_MOUSE (1-437): 0: 697: 40.73
+	Hs
		997033 SH2D3_HUMAN (333-582): 1.16e-39: 156: 23.55		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Mm
		59666 A2AM67_MOUSE (191-575): 2.17e-43: 162: 14.72		TBA1A_MOUSE (1-439): 0: 715: 99.09
+	Hs
		594031 NCK1_HUMAN (360-575): 1.56e-41: 155: 18.30		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		699692 P85A_HUMAN (300-581): 8.31e-38: 151: 15.31		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		136425 P85B_HUMAN (292-581): 8.3e-32: 132: 17.15		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		136257 P85B_HUMAN (292-581): 8.3e-32: 132: 17.15		TBB5_HUMAN (1-439): 0: 699: 41.00