HitPredict

Interactor 1: DMWD (Q09019)
Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (Protein 59) (Protein DMR-N9)
Gene: DMWD

Interactor 2: WDR6 (Q9NNW5)
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WD repeat-containing protein 6)
Gene: WDR6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 674 Hs			1 1121
+	Hs
		792967 LIS1_HUMAN (61-356): 1.01e-54: 194: 12.09		RACK1_HUMAN (196-523): 2.91e-47: 173: 17.21
+	Sp
		999838 TUP11_SCHPO (7-405): 6.76e-65: 227: 12.71		TUP11_SCHPO (759-1119): 9.81e-29: 125: 16.94
+	Hs
		929392 RACK1_HUMAN (160-449): 1.04e-49: 178: 13.61		RACK1_HUMAN (196-523): 2.91e-47: 173: 17.21
+	Hs
		929730 RACK1_HUMAN (160-449): 1.04e-49: 178: 13.61		FBW1A_HUMAN (30-284): 7.71e-34: 140: 13.41
+	Sp
		999842 TUP11_SCHPO (7-405): 6.76e-65: 227: 12.71		TUP12_SCHPO (126-327): 1.91e-15: 82.9: 17.96
+	Hs
		929692 RACK1_HUMAN (160-449): 1.04e-49: 178: 13.61		NLE1_HUMAN (2-141): 9.17e-25: 111: 8.05
+	Sp
		140390 TAF73_SCHPO (214-446): 5.65e-57: 206: 18.70		TAF5_SCHPO (168-455): 3.06e-14: 79.4: 20.65
+	Mm
		925836 LIS1_MOUSE (61-356): 7.16e-55: 195: 12.09		LIS1_MOUSE (865-1100): 3.49e-17: 87.4: 12.71
+	Sc
		635569 GBLP_YEAST (246-527): 9.07e-48: 172: 18.71		PWP2_YEAST (1-272): 1.26e-17: 90.9: 12.30
+	Hs
		1240442 POC1A_HUMAN (52-353): 4.66e-51: 184: 13.25		POC1B_HUMAN (701-1007): 2.63e-12: 72.5: 15.43
+	Hs
		792949 LIS1_HUMAN (61-356): 1.01e-54: 194: 12.09		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53
+	Hs
		929603 RACK1_HUMAN (160-449): 1.04e-49: 178: 13.61		FBXW7_HUMAN (603-914): 3.98e-13: 76: 13.75
+	Hs
		254111 FBXW7_HUMAN (75-349): 3.2e-27: 119: 7.77		WDR1_HUMAN (538-1119): 1.07e-31: 134: 9.41
+	Hs
		929579 RACK1_HUMAN (160-449): 1.04e-49: 178: 13.61		POC1B_HUMAN (701-1007): 2.63e-12: 72.5: 15.43
+	Hs
		929610 RACK1_HUMAN (160-449): 1.04e-49: 178: 13.61		SNR40_HUMAN (200-348): 7.65e-10: 64: 26.58
+	Hs
		903109 RACK1_HUMAN (160-449): 1.04e-49: 178: 13.61		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53
+	Hs
		197071 PRP4_HUMAN (62-311): 1.14e-28: 122: 14.40		SNR40_HUMAN (200-348): 7.65e-10: 64: 26.58
+	Hs
		196984 PRP4_HUMAN (62-311): 1.14e-28: 122: 14.40		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53