HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: RENT1 (Q92900)
Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1)
Gene: UPF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30110629, 33742100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 2 others more... GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2414 Hs			1 1129
+	Hs
		1272406 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		RENT1_HUMAN (1-1129): 0: 1604: 100.00
+	Hs
		999109 EP300_HUMAN (1-2414): 0: 1113: 100.00		MOV10_HUMAN (324-950): 2.67e-157: 496: 23.12
+	Hs
		846686 EP300_HUMAN (1-2414): 0: 1113: 100.00		DNA2_HUMAN (283-913): 7.58e-150: 478: 24.60
+	Hs
		164363 TRI66_HUMAN (268-1197): 1.08e-40: 168: 12.26		DNA2_HUMAN (283-913): 7.58e-150: 478: 24.60
+	Sc
		728738 BDF1_YEAST (1041-1152): 6.84e-09: 63.2: 37.61		SEN1_YEAST (286-929): 7.8e-159: 523: 25.46