HitPredict

Interactor 1: P70012 (P70012)
Nuclear mitotic apparatus protein 1 S homeolog (Nuclear/mitotic apparatus protein)
Gene: numa1.S

Interactor 2: Q90X96 (Q90X96)
RING-type E3 ubiquitin transferase (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BRCA1)
Gene: brca1.L

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	17081976
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2253 Xl			1 1579
+	Xl
		999730 P70012_XENLA (1-2253): 1.03e-172: 588: 100.00		Q90X95_XENLA (9-390): 3.83e-31: 134: 18.03
+	Hs
		623511 CP250_HUMAN (147-2223): 3.4e-85: 314: 12.37		RO52_HUMAN (15-412): 1.33e-92: 311: 13.72
+	Hs
		1134663 NUMA1_HUMAN (757-2249): 1.72e-45: 184: 11.23		TOPB1_HUMAN (755-1577): 6.09e-119: 412: 11.25
+	Hs
		552852 TPR_HUMAN (28-580): 3.62e-17: 91.2: 10.91		TOPB1_HUMAN (755-1577): 6.09e-119: 412: 11.25
+	Hs
		1129593 NUMA1_HUMAN (757-2249): 1.72e-45: 184: 11.23		MDC1_HUMAN (297-1528): 8.31e-77: 285: 10.64
+	Hs
		1141792 EEA1_HUMAN (31-846): 2.65e-34: 147: 10.54		MCPH1_HUMAN (995-1578): 5.25e-76: 273: 14.55
+	Hs
		799124 NUMA1_HUMAN (757-2249): 1.72e-45: 184: 11.23		BRCA1_HUMAN (1-763): 6.82e-59: 227: 23.05
+	Hs
		552748 TPR_HUMAN (28-580): 3.62e-17: 91.2: 10.91		RO52_HUMAN (15-412): 1.33e-92: 311: 13.72
+	Hs
		773006 MYH9_HUMAN (1233-1915): 1.33e-28: 128: 10.84		TRIM6_HUMAN (10-394): 6.63e-80: 274: 12.02
+	Hs
		798843 CENPF_HUMAN (518-2235): 1.02e-42: 175: 10.63		BRCA1_HUMAN (1-763): 6.82e-59: 227: 23.05
+	Hs
		773270 MYH10_HUMAN (1064-1791): 1.56e-25: 118: 13.45		TRIM6_HUMAN (10-394): 6.63e-80: 274: 12.02
+	Hs
		563033 MYH6_HUMAN (1555-2192): 1.55e-21: 105: 8.67		TRIM6_HUMAN (10-394): 6.63e-80: 274: 12.02
+	Hs
		556952 MYH7_HUMAN (22-445): 2.79e-15: 84.7: 11.86		TRIM6_HUMAN (10-394): 6.63e-80: 274: 12.02
+	Hs
		772651 MYH9_HUMAN (1233-1915): 1.33e-28: 128: 10.84		BRCA1_HUMAN (1-763): 6.82e-59: 227: 23.05
+	Hs
		773114 MYH10_HUMAN (1064-1791): 1.56e-25: 118: 13.45		BRCA1_HUMAN (1-763): 6.82e-59: 227: 23.05
+	Hs
		1134694 NUMA1_HUMAN (757-2249): 1.72e-45: 184: 11.23		BARD1_HUMAN (12-354): 3.81e-36: 150: 15.28
+	Hs
		552765 TPR_HUMAN (28-580): 3.62e-17: 91.2: 10.91		BRCA1_HUMAN (1-763): 6.82e-59: 227: 23.05
+	Hs
		1089224 CNTRL_HUMAN (10-628): 2.73e-15: 85: 11.47		TRI26_HUMAN (11-273): 1.23e-53: 199: 11.52
+	Hs
		773005 MYH9_HUMAN (1233-1915): 1.33e-28: 128: 10.84		TRI31_HUMAN (15-160): 1.75e-19: 95: 23.97
+	Hs
		773269 MYH10_HUMAN (1064-1791): 1.56e-25: 118: 13.45		TRI31_HUMAN (15-160): 1.75e-19: 95: 23.97