HitPredict

Interactor 1: TUP11 (Q09715)
Transcriptional repressor tup11
Gene: TUP11

Interactor 2: FEP1 (Q10134)
Iron-sensing transcriptional repressor (Transcription factor gaf2) (Gaf-2)
Gene: FEP1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.642

Property	Details
Experiments	14668334, 15866870, 21421748
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 614 Sp			1 564
+	Hs
		620569 TBL1R_HUMAN (13-474): 1.1e-53: 193: 10.33		GATA3_HUMAN (5-168): 1.15e-25: 111: 24.10
+	Hs
		620419 TBL1R_HUMAN (13-474): 1.1e-53: 193: 10.33		GATA2_HUMAN (102-258): 8.39e-24: 106: 25.61
+	Hs
		245561 TBL1X_HUMAN (13-474): 3.37e-50: 184: 9.53		GATA3_HUMAN (5-168): 1.15e-25: 111: 24.10
+	Hs
		245560 TBL1X_HUMAN (13-474): 3.37e-50: 184: 9.53		GATA2_HUMAN (102-258): 8.39e-24: 106: 25.61
+	Hs
		799000 TBL1R_HUMAN (13-474): 1.1e-53: 193: 10.33		GATA4_HUMAN (128-258): 3.53e-16: 83.1: 23.81
+	Hs
		245558 TBL1X_HUMAN (13-474): 3.37e-50: 184: 9.53		GATA1_HUMAN (22-155): 2.26e-10: 64.9: 17.16
+	Rn
		803059 GBB2_RAT (459-613): 6.82e-25: 107: 20.76		GATA4_RAT (128-258): 1.11e-16: 84.6: 24.66
+	Hs
		798837 GBB2_HUMAN (459-613): 1.49e-23: 103: 20.76		GATA4_HUMAN (128-258): 3.53e-16: 83.1: 23.81
+	Sc
		561850 TUP1_YEAST (477-613): 5.45e-25: 112: 19.13		DAL80_YEAST (11-139): 5.2e-13: 71.5: 21.68
+	Hs
		798841 RACK1_HUMAN (475-608): 9.62e-18: 86.3: 38.52		GATA4_HUMAN (128-258): 3.53e-16: 83.1: 23.81