Protein: SGSM1
Small G protein signaling modulator 1 (RUN and TBC1 domain-containing protein 2)

Gene: SGSM1
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q2NKQ1

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0030659 - cytoplasmic vesicle membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1086164

CETN1
Centrin-1

7

8

High-throughput

0.749

High

832905

CETN2
Centrin-2

5

8

High-throughput

0.725

High

181627

CETN3
Centrin-3

4

7

High-throughput

0.704

High

1179214

OCAD1
OCIA domain-containing protein 1

1

2

High-throughput

0.536

High

241840

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.515

High

384426

CRYAA
Alpha-crystallin A chain

1

2

High-throughput

0.515

High

422214

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.515

High

791428

SYUA
Alpha-synuclein

1

1

High-throughput

0.515

High

889995

PSN1
Presenilin-1

1

1

High-throughput

0.515

High

890741

PSN2
Presenilin-2

1

1

High-throughput

0.515

High

896771

DYN2
Dynamin-2

1

3

High-throughput

0.515

High

927325

ATX1
Ataxin-1

1

1

High-throughput

0.515

High

1179210

OPTN
Optineurin

1

5

High-throughput

0.515

High

1179212

RANB3
Ran-binding protein 3

1

0

High-throughput

0.513

High

167608

GIPC1
PDZ domain-containing protein GIPC1

1

0

High-throughput

0.493

High

361266

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.493

High

843607

HD
Huntingtin

1

0

High-throughput

0.493

High

1160469

SMN
Survival motor neuron protein

1

0

High-throughput

0.493

High

1179208

Q8IVP1
SH3-domain GRB2-like 3, isoform CRA_a

1

0

High-throughput

0.493

High

1144244

PGFRL
Platelet-derived growth factor receptor-like protein

1

2

High-throughput

0.489

High

1179209

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

3

High-throughput

0.489

High

1179206

RN123
E3 ubiquitin-protein ligase RNF123

1

4

High-throughput

0.479

High

361697

F13A
Coagulation factor XIII A chain

1

3

High-throughput

0.470

High

106033

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

888524

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1179213

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

1

0

High-throughput

0.279

Low

47335

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

231232

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.268

Low

1179207

Q86V38
Atrophin 1

1

0

High-throughput

0.268

Low

1179211

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025