Protein: NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (Complex I-15 kDa) (CI-15 kDa) (NADH-ubiquinone oxidoreductase 15 kDa subunit)

Gene: NDUS5, NDUFS5
Organism: Homo sapiens
Interactions: 122
UniProt ID: O43920

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005758 - mitochondrial intermembrane space
GO:0006120 - mitochondrial electron transport, NADH to ubiquinone
GO:0008137 - NADH dehydrogenase (ubiquinone) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

231278

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

3

1

High-throughput

0.861

High

231194

NU4M
NADH-ubiquinone oxidoreductase chain 4

2

1

High-throughput

0.811

High

231195

NU5M
NADH-ubiquinone oxidoreductase chain 5

2

1

High-throughput

0.811

High

223574

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

2

0

High-throughput

0.770

High

231188

AIFM1
Apoptosis-inducing factor 1, mitochondrial

4

0

High-throughput

0.664

High

231187

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

0

High-throughput

0.656

High

231196

NU6M
NADH-ubiquinone oxidoreductase chain 6

1

0

High-throughput

0.656

High

231177

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

3

0

High-throughput

0.646

High

231276

NDUBB
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

3

0

High-throughput

0.646

High

231179

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

3

0

High-throughput

0.638

High

231201

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

3

0

High-throughput

0.634

High

231223

NDUA6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6

3

0

Small-scale

0.634

High

231285

CIA30
Complex I intermediate-associated protein 30, mitochondrial

3

0

Small-scale

0.634

High

127431

NDUS8
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

2

0

High-throughput

0.602

High

209711

NDUS4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

2

0

High-throughput

0.602

High

231175

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

2

0

High-throughput

0.602

High

231176

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

2

0

High-throughput

0.602

High

231182

NDUB6
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6

2

0

High-throughput

0.602

High

231184

NDUB4
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4

2

0

High-throughput

0.602

High

231185

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

2

0

High-throughput

0.602

High

231186

NDUA7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

2

0

High-throughput

0.602

High

231189

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

2

0

High-throughput

0.602

High

231193

NU1M
NADH-ubiquinone oxidoreductase chain 1

2

0

High-throughput

0.602

High

231200

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

2

0

High-throughput

0.602

High

231204

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

2

0

High-throughput

0.602

High

231215

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

2

0

High-throughput

0.602

High

231222

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

2

0

High-throughput

0.602

High

231231

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

2

0

High-throughput

0.602

High

231256

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

2

0

High-throughput

0.602

High

231269

ACAD9
Complex I assembly factor ACAD9, mitochondrial

2

0

High-throughput

0.602

High

231273

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

2

0

High-throughput

0.602

High

231277

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

2

0

High-throughput

0.602

High

231281

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

2

0

High-throughput

0.602

High

231287

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

2

0

High-throughput

0.602

High

231240

NDUAB
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

2

0

High-throughput

0.585

High

231251

FXRD1
FAD-dependent oxidoreductase domain-containing protein 1

2

0

Small-scale

0.585

High

231192

ESR1
Estrogen receptor

2

1

High-throughput

0.521

High

66091

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.513

High

156179

CO72L
Cytochrome c oxidase subunit 7A2-like, mitochondrial

1

0

High-throughput

0.513

High

183792

NDUA1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1

1

0

High-throughput

0.513

High

223674

NDUB3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

1

0

High-throughput

0.513

High

223771

NDUA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

1

0

High-throughput

0.513

High

231183

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

0

High-throughput

0.513

High

231198

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

231205

AMPL
Cytosol aminopeptidase

1

0

High-throughput

0.513

High

231206

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

0

High-throughput

0.513

High

231207

CASPE
Caspase-14

1

0

High-throughput

0.513

High

231213

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.513

High

231230

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

1

0

High-throughput

0.513

High

231238

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.513

High

231241

T126B
Complex I assembly factor TMEM126B, mitochondrial

1

0

High-throughput

0.513

High

231243

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

231245

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.513

High

231253

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

0

High-throughput

0.513

High

231258

NDUF3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3

1

0

High-throughput

0.513

High

231259

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.513

High

231178

NDUB1
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1

1

0

High-throughput

0.493

High

231214

SPB4
Serpin B4

1

1

High-throughput

0.489

High

231216

SPB8
Serpin B8

1

1

High-throughput

0.489

High

231242

SPA12
Serpin A12

1

2

High-throughput

0.489

High

231235

MRM1
rRNA methyltransferase 1, mitochondrial

1

1

High-throughput

0.479

High

137572

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

231199

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

231220

NDUA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

1

0

High-throughput

0.458

High

231224

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

231228

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

231229

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

231254

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.458

High

231260

TR61B
tRNA

1

0

High-throughput

0.458

High

231263

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

231265

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.458

High

231266

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

0

High-throughput

0.458

High

231267

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

231270

SFXN1
Sideroflexin-1

1

0

High-throughput

0.458

High

231271

MRM3
rRNA methyltransferase 3, mitochondrial

1

0

High-throughput

0.458

High

231274

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.458

High

231275

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

231190

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

231197

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

231211

NR4A2
Nuclear receptor subfamily 4 group A member 2

1

1

High-throughput

0.437

High

231268

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

231210

HD
Huntingtin

2

0

High-throughput

0.306

High

231180

WBP4
WW domain-binding protein 4

1

0

High-throughput

0.279

Low

231181

ACL6B
Actin-like protein 6B

1

0

High-throughput

0.279

Low

231202

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

0

High-throughput

0.279

Low

231203

LORI
Loricrin

1

0

High-throughput

0.279

Low

231208

MYH9
Myosin-9

1

0

High-throughput

0.279

Low

231209

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.279

Low

231212

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

0

High-throughput

0.279

Low

231217

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.279

Low

231221

MANF
Mesencephalic astrocyte-derived neurotrophic factor

1

0

High-throughput

0.279

Low

231225

PKP1
Plakophilin-1

1

0

High-throughput

0.279

Low

231234

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.279

Low

231236

SBSN
Suprabasin

1

0

High-throughput

0.279

Low

231237

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

231246

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

0

High-throughput

0.279

Low

231249

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

231250

ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b

1

0

High-throughput

0.279

Low

231252

CPNS2
Calpain small subunit 2

1

0

High-throughput

0.279

Low

231255

GSDMA
Gasdermin-A

1

0

High-throughput

0.279

Low

231257

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

0

High-throughput

0.279

Low

231261

LOXE3
Hydroperoxide isomerase ALOXE3

1

0

High-throughput

0.279

Low

231279

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.279

Low

231282

CBPA4
Carboxypeptidase A4

1

0

High-throughput

0.279

Low

231286

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.279

Low

231232

SGSM1
Small G protein signaling modulator 1

1

0

High-throughput

0.268

Low

231233

SPAS1
Spermatogenesis-associated serine-rich protein 1

1

0

High-throughput

0.268

Low

231272

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

0

High-throughput

0.268

Low

231227

T132D
Transmembrane protein 132D

1

0

Small-scale

0.251

Low

231262

S13A1
Solute carrier family 13 member 1

1

0

Small-scale

0.251

Low

231191

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

231218

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.249

Low

231219

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

High-throughput

0.249

Low

231244

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.249

Low

231264

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.249

Low

231280

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

231226

MFS10
Major facilitator superfamily domain-containing protein 10

1

0

High-throughput

0.232

Low

231239

S35E3
Solute carrier family 35 member E3

1

0

High-throughput

0.232

Low

231247

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

0

High-throughput

0.232

Low

231248

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

0

High-throughput

0.232

Low

231283

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.232

Low

231284

S35A3
UDP-N-acetylglucosamine transporter

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025