Protein: ITA8
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]

Gene: ITA8, ITGA8
Organism: Homo sapiens
Interactions: 62
UniProt ID: P53708

Gene Ontology (top 5):
GO:0001656 - metanephros development
GO:0001822 - kidney development
GO:0005178 - integrin binding
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

922824

BTNL8
Butyrophilin-like protein 8

3

11

High-throughput

0.861

High

431758

ITB1
Integrin beta-1

2

20

Small-scale

0.789

High

731830

CEAM8
Cell adhesion molecule CEACAM8

1

7

High-throughput

0.691

High

922815

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

6

High-throughput

0.667

High

922828

TMM25
Transmembrane protein 25

2

2

High-throughput

0.628

High

922837

CALR3
Calreticulin-3

2

10

High-throughput

0.611

High

922816

TAZ
Tafazzin

3

3

High-throughput

0.609

High

922822

SUSD4
Sushi domain-containing protein 4

3

3

High-throughput

0.609

High

533628

CLUS
Clusterin

2

0

High-throughput

0.602

High

922810

NAR3
Ecto-ADP-ribosyltransferase 3

2

2

High-throughput

0.584

High

922848

DKKL1
Dickkopf-like protein 1

2

1

High-throughput

0.574

High

922825

NPNT
Nephronectin

1

3

Small-scale

0.561

High

351818

BY55
CD160 antigen

1

4

High-throughput

0.536

High

480748

LEG1
Galectin-1

1

20

High-throughput

0.536

High

593317

PGFRA
Platelet-derived growth factor receptor alpha

1

7

High-throughput

0.536

High

922809

BST1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2

1

1

High-throughput

0.536

High

922814

DSC3
Desmocollin-3

1

5

High-throughput

0.536

High

922821

LY65C
Lymphocyte antigen 6 complex locus protein G5c

1

1

High-throughput

0.536

High

922829

ZDH17
Palmitoyltransferase ZDHHC17

1

1

High-throughput

0.536

High

922831

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

2

High-throughput

0.536

High

922834

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

1

4

High-throughput

0.536

High

922838

TAFA4
Chemokine-like protein TAFA-4

1

4

High-throughput

0.536

High

922839

GML
Glycosyl-phosphatidylinositol-anchored molecule-like protein

1

1

High-throughput

0.536

High

922841

GPC5C
G-protein coupled receptor family C group 5 member C

1

1

High-throughput

0.536

High

922842

PICK1
PRKCA-binding protein

1

4

High-throughput

0.536

High

922843

ZDH18
Palmitoyltransferase ZDHHC18

1

1

High-throughput

0.536

High

922846

NPAP1
Nuclear pore-associated protein 1

1

2

High-throughput

0.536

High

922847

FBX2
F-box only protein 2

1

11

High-throughput

0.536

High

922849

ZNRF3
E3 ubiquitin-protein ligase ZNRF3

1

5

High-throughput

0.536

High

922853

PCDGA
Protocadherin gamma-A10

1

4

High-throughput

0.536

High

922854

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

2

High-throughput

0.536

High

2097

TVA20
T cell receptor alpha variable 20

1

2

High-throughput

0.514

High

922830

TPPC5
Trafficking protein particle complex subunit 5

1

0

High-throughput

0.513

High

922835

NGBR
Dehydrodolichyl diphosphate synthase complex subunit NUS1

1

0

High-throughput

0.513

High

922845

CLDN1
Claudin domain-containing protein 1

1

0

High-throughput

0.513

High

142206

CCL22
C-C motif chemokine 22

1

1

High-throughput

0.489

High

625991

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

1

1

High-throughput

0.489

High

922813

EP3A
Epididymal secretory protein E3-alpha

1

4

High-throughput

0.489

High

922817

DB136
Defensin beta 136

1

1

High-throughput

0.489

High

922818

DB135
Beta-defensin 135

1

1

High-throughput

0.489

High

922826

SG1D4
Secretoglobin family 1D member 4

1

2

High-throughput

0.489

High

922827

HOOK3
Protein Hook homolog 3

1

7

High-throughput

0.489

High

922833

LCN9
Epididymal-specific lipocalin-9

1

6

High-throughput

0.489

High

922836

LCFC1
Sperm-egg fusion protein LLCFC1

1

3

High-throughput

0.489

High

922844

DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

1

1

High-throughput

0.489

High

922850

HIG1A
HIG1 domain family member 1A, mitochondrial

1

1

High-throughput

0.489

High

922851

MAN1
Inner nuclear membrane protein Man1

1

2

High-throughput

0.489

High

922852

DHRS7
Dehydrogenase/reductase SDR family member 7

1

1

High-throughput

0.489

High

922855

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

2

High-throughput

0.489

High

922811

PTC1
Protein patched homolog 1

1

5

High-throughput

0.479

High

521599

H14
Histone H1.4

1

4

High-throughput

0.470

High

553796

KCRU
Creatine kinase U-type, mitochondrial

1

1

High-throughput

0.470

High

908347

HDGF
Hepatoma-derived growth factor

1

0

High-throughput

0.458

High

922812

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.458

High

222258

PSCA
Prostate stem cell antigen

1

4

High-throughput

0.445

High

922819

DB109
Beta-defensin 109B

1

3

High-throughput

0.407

High

922820

Q5J1K9
Mono-ADP-ribosyltransferase 3 variant Ia

1

2

High-throughput

0.407

High

922808

LIPR1
Inactive pancreatic lipase-related protein 1

2

0

High-throughput

0.328

High

244050

SUSD5
Sushi domain-containing protein 5

1

0

High-throughput

0.279

Low

922823

LCTL
Lactase-like protein

1

0

High-throughput

0.279

Low

922832

THEM6
Protein THEM6

1

0

High-throughput

0.279

Low

922840

SIAE
Sialate O-acetylesterase

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025