Protein: PPCS
Phosphopantothenate--cysteine ligase (EC 6.3.2.51) (Phosphopantothenoylcysteine synthetase) (PPC synthetase)

Gene: PPCS
Organism: Homo sapiens
Interactions: 33
UniProt ID: Q9HAB8

Gene Ontology (top 5):
GO:0003015 - heart process
GO:0004632 - phosphopantothenate--cysteine ligase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1437489

PPCS
Phosphopantothenate--cysteine ligase

2

2

High-throughput

0.783

High

391089

TRFL
Lactotransferrin

1

0

High-throughput

0.513

High

733439

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

762091

MPI
Mannose-6-phosphate isomerase

1

0

High-throughput

0.513

High

834264

PLPL4
Patatin-like phospholipase domain-containing protein 4

1

0

High-throughput

0.513

High

1279583

SPRE2
Sprouty-related, EVH1 domain-containing protein 2

1

0

High-throughput

0.513

High

1437490

DMBT1
Scavenger receptor cysteine-rich domain-containing protein DMBT1

1

0

High-throughput

0.513

High

1437492

PZRN3
E3 ubiquitin-protein ligase PDZRN3

1

0

High-throughput

0.513

High

1315223

TRM44
Probable tRNA

1

0

High-throughput

0.493

High

192962

CLOCK
Circadian locomoter output cycles protein kaput

1

0

High-throughput

0.458

High

386246

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

589730

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

696550

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

897400

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

1255595

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1334940

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

598776

ANFB
Natriuretic peptides B

1

0

High-throughput

0.426

High

1392410

SYMM
Methionine--tRNA ligase, mitochondrial

1

0

High-throughput

0.426

High

1437493

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.426

High

49600

GXLT2
Glucoside xylosyltransferase 2

1

0

High-throughput

0.279

Low

286589

SG2A1
Mammaglobin-B

1

0

High-throughput

0.279

Low

366210

HPT
Haptoglobin

1

0

High-throughput

0.279

Low

1083504

BST1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2

1

0

High-throughput

0.279

Low

1248858

CE046
Uncharacterized protein C5orf46

1

0

High-throughput

0.279

Low

1351343

BPIB1
BPI fold-containing family B member 1

1

0

High-throughput

0.279

Low

1429183

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.279

Low

769217

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1383682

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

330325

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.232

Low

379778

IGHA2
Immunoglobulin heavy constant alpha 2

1

0

High-throughput

0.232

Low

1311931

FBX16
F-box only protein 16

1

0

High-throughput

0.232

Low

1437491

S13A4
Solute carrier family 13 member 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025