Interactor 1: CSN4 (Q9V345)
COP9 signalosome complex subunit 4 (Dch4) (Signalosome subunit 4)
Gene: CSN4

Interactor 2: CSN7 (Q9V4S8)
COP9 signalosome complex subunit 7 (Dch7) (Signalosome subunit 7)
Gene: CSN7

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.911

The method score is based on:

Property Details
Experiments 10531038, 25119050, 37061542, 22036573, 38944040
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CSN4_RPN5_eIF3a~CSN7_HB_subdom, CSN4_RPN5_eIF3a~CSN7a_helixI, CSN4_RPN5_eIF3a~PCI, CSN7_HB_subdom~PCI, PCI~PCI, PCI~PSMD12-CSN4_N
Common GO terms GO:0000338 - protein deneddylation
GO:0005737 - cytoplasm
GO:0007281 - germ cell development
GO:0008180 - COP9 signalosome
GO:0036099 - female germ-line stem cell population maintenance
and 2 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 407
Dm

1 278
+ Hs
+ Hs
+ Dm
+ At
+ At
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Ce
+ An
+ Ce
+ An
+ Dm
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025