HitPredict

Interactor 1: PSA2 (P40301)
Proteasome subunit alpha type-2 (PROS-Dm25) (Proteasome 25 kDa subunit)
Gene: Prosalpha2

Interactor 2: CSN4 (Q9V345)
COP9 signalosome complex subunit 4 (Dch4) (Signalosome subunit 4)
Gene: CSN4

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PSMD12-CSN4_N~Proteasome
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 234 Dm			1 407
+	Sp
		314465 PSA2_SCHPO (3-233): 1.97e-107: 311: 58.20		RPN6_SCHPO (4-400): 3.77e-84: 265: 13.69
+	Dm
		1267331 PSA5_DROME (1-233): 1.18e-97: 286: 30.71		PSD11_DROME (10-402): 6.46e-91: 282: 13.68
+	Hs
		127885 PSA5_HUMAN (1-233): 1.1e-98: 288: 31.38		PSD11_HUMAN (4-402): 3.64e-89: 277: 13.48
+	Hs
		128155 PSA5_HUMAN (1-233): 1.1e-98: 288: 31.38		PSD12_HUMAN (29-399): 1.9e-87: 274: 19.19
+	Dm
		821845 PSA2_DROME (1-234): 1.81e-95: 280: 100.00		PSD11_DROME (10-402): 6.46e-91: 282: 13.68
+	Hs
		127880 PSA2_HUMAN (1-233): 9.16e-96: 281: 78.11		PSD11_HUMAN (4-402): 3.64e-89: 277: 13.48
+	Hs
		128149 PSA2_HUMAN (1-233): 9.16e-96: 281: 78.11		PSD12_HUMAN (29-399): 1.9e-87: 274: 19.19
+	Hs
		127879 PSA1_HUMAN (1-233): 5.13e-92: 272: 30.67		PSD11_HUMAN (4-402): 3.64e-89: 277: 13.48
+	Hs
		127830 PSA7_HUMAN (6-231): 6.72e-91: 269: 36.52		PSD11_HUMAN (4-402): 3.64e-89: 277: 13.48
+	Hs
		127916 PSA6_HUMAN (3-233): 4.89e-91: 269: 32.49		PSD11_HUMAN (4-402): 3.64e-89: 277: 13.48
+	Hs
		128148 PSA1_HUMAN (1-233): 5.13e-92: 272: 30.67		PSD12_HUMAN (29-399): 1.9e-87: 274: 19.19
+	Hs
		128102 PSA7_HUMAN (6-231): 6.72e-91: 269: 36.52		PSD12_HUMAN (29-399): 1.9e-87: 274: 19.19
+	Hs
		128192 PSA6_HUMAN (3-233): 4.89e-91: 269: 32.49		PSD12_HUMAN (29-399): 1.9e-87: 274: 19.19
+	Hs
		954777 PSA6_HUMAN (3-233): 4.89e-91: 269: 32.49		CSN2_HUMAN (1-388): 1.34e-87: 274: 13.33
+	Sc
		735970 PSA5_YEAST (1-233): 2.64e-91: 270: 31.12		RPN6_YEAST (13-400): 3.5e-75: 241: 12.41
+	Sc
		735969 PSA5_YEAST (1-233): 2.64e-91: 270: 31.12		RPN5_YEAST (32-399): 5.82e-72: 234: 19.17
+	Sc
		661575 PSA2_YEAST (3-216): 2.65e-81: 245: 59.91		RPN6_YEAST (13-400): 3.5e-75: 241: 12.41
+	Sc
		661573 PSA2_YEAST (3-216): 2.65e-81: 245: 59.91		RPN5_YEAST (32-399): 5.82e-72: 234: 19.17
+	Sc
		661449 PSA3_YEAST (1-230): 7.09e-50: 165: 39.75		RPN6_YEAST (13-400): 3.5e-75: 241: 12.41
+	Sc
		661447 PSA3_YEAST (1-230): 7.09e-50: 165: 39.75		RPN5_YEAST (32-399): 5.82e-72: 234: 19.17