Protein: IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappaB kinase subunit beta) (EC 2.7.11.10) (Cactus kinase IKK) (IKK-like protein) (Immune response deficient protein 5) (Lipopolysaccharide-activated kinase) (DLAK)

Gene: IKKB, IKKbeta
Organism: Drosophila melanogaster
Interactions: 174
UniProt ID: Q9VEZ5

Gene Ontology (top 5):
GO:0002230 - positive regulation of defense response to virus by host
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1276719

NFKB1
Nuclear factor NF-kappa-B p110 subunit

3

20

Small-scale

0.861

High

1365053

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

3

20

Small-scale

0.840

High

974293

CACT
NF-kappa-B inhibitor cactus

2

20

Small-scale

0.834

High

1325883

NEMO
NF-kappa-B essential modulator

4

0

Small-scale

0.665

High

783398

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

1

High-throughput

0.618

High

1359962

ANLN
Anillin

1

2

High-throughput

0.618

High

1362718

ANKHM
Ankyrin repeat and KH domain-containing protein mask

1

2

High-throughput

0.618

High

1365102

RHGF
Rho GTPase-activating protein Graf

1

4

High-throughput

0.618

High

1365071

Q9VPY3
Charon

1

0

High-throughput

0.586

High

527111

SPTCA
Spectrin alpha chain

1

5

High-throughput

0.553

High

978465

NONA
Protein no-on-transient A

1

6

High-throughput

0.553

High

1358452

Q9V3E7
LD24793p

1

3

High-throughput

0.553

High

1365063

Q9VJJ9
FI20237p1

1

2

High-throughput

0.553

High

1365103

X2JFU3
Uncharacterized protein, isoform E

1

4

High-throughput

0.553

High

115596

M9PFI0
CCR4-NOT transcription complex subunit 4, isoform J

1

0

High-throughput

0.517

High

1365055

Q9VG33
Sulfurtransferase

1

0

High-throughput

0.517

High

55825

A1ZB77
Uncharacterized protein, isoform J

1

2

High-throughput

0.479

High

114282

M9PBW9
Rhea, isoform G

1

19

High-throughput

0.479

High

115942

M9PGZ8
Smrter, isoform G

1

20

High-throughput

0.479

High

116344

M9PI17
Aldo-keto reductase 1B, isoform D

1

1

High-throughput

0.479

High

137773

CH60A
Heat shock protein 60A

1

13

High-throughput

0.479

High

220663

CTBP
C-terminal-binding protein

1

3

High-throughput

0.479

High

248464

KPYK
Pyruvate kinase

1

2

High-throughput

0.479

High

332300

EF1B
Probable elongation factor 1-beta

1

3

High-throughput

0.479

High

332639

HSP68
Heat shock protein 68

1

16

High-throughput

0.479

High

365410

HSP71
Major heat shock 70 kDa protein Ab

1

16

High-throughput

0.479

High

387950

CYC1
Cytochrome c-1

1

1

High-throughput

0.479

High

415614

TBA1
Tubulin alpha-1 chain

1

16

High-throughput

0.479

High

415638

TBA2
Tubulin alpha-2 chain

1

15

High-throughput

0.479

High

415661

TBA3
Tubulin alpha-3 chain

1

16

High-throughput

0.479

High

444599

EF1A1
Elongation factor 1-alpha 1

1

8

High-throughput

0.479

High

445208

TBB3
Tubulin beta-3 chain

1

20

High-throughput

0.479

High

505090

HSP7D
Heat shock 70 kDa protein cognate 4

1

13

High-throughput

0.479

High

520043

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.479

High

525374

EF2
Eukaryotic translation elongation factor 2

1

2

High-throughput

0.479

High

530327

ATNA
Sodium/potassium-transporting ATPase subunit alpha

1

2

High-throughput

0.479

High

547642

DORS
Embryonic polarity protein dorsal

1

18

High-throughput

0.479

High

567406

CATA
Catalase

1

1

High-throughput

0.479

High

593960

NCD
Protein claret segregational

1

7

High-throughput

0.479

High

599219

FOSLA
Transcription factor kayak, isoforms A/B/F

1

6

High-throughput

0.479

High

611119

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

1

3

High-throughput

0.479

High

613202

MA205
205 kDa microtubule-associated protein

1

2

High-throughput

0.479

High

621750

PHB1
Prohibitin 1

1

2

High-throughput

0.479

High

669799

HSP7A
Heat shock 70 kDa protein cognate 1

1

13

High-throughput

0.479

High

669826

BIP
Endoplasmic reticulum chaperone BiP

1

16

High-throughput

0.479

High

669856

HSP7E
Heat shock 70 kDa protein cognate 5

1

20

High-throughput

0.479

High

723155

ATPA
ATP synthase subunit alpha, mitochondrial

1

4

High-throughput

0.479

High

799769

CADF
Cofilin/actin-depolymerizing factor homolog

1

6

High-throughput

0.479

High

803301

RL11
Large ribosomal subunit protein uL5

1

2

High-throughput

0.479

High

820669

TCPG
T-complex protein 1 subunit gamma

1

16

High-throughput

0.479

High

902249

TBB2
Tubulin beta-2 chain

1

20

High-throughput

0.479

High

954856

MIC60
MICOS complex subunit Mic60

1

19

High-throughput

0.479

High

983470

EYA
Developmental protein eyes absent

1

2

Small-scale

0.479

High

984872

ATPB
ATP synthase subunit beta, mitochondrial

1

4

High-throughput

0.479

High

1000614

Q0E8J0
MEP-1, isoform A

1

1

High-throughput

0.479

High

1097637

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

1

High-throughput

0.479

High

1097947

CP190
Centrosome-associated zinc finger protein Cp190

1

8

High-throughput

0.479

High

1098170

TBB1
Tubulin beta-1 chain

1

20

High-throughput

0.479

High

1099824

NLP
Nucleoplasmin-like protein

1

3

High-throughput

0.479

High

1178578

NUP50
Nuclear pore complex protein Nup50

1

1

High-throughput

0.479

High

1179637

Q7K3J0
T-complex protein 1 subunit theta

1

20

High-throughput

0.479

High

1180662

Q7KKI0
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.479

High

1181039

Q7KMQ0
26S proteasome regulatory subunit 7

1

4

High-throughput

0.479

High

1182227

Q7KTW5
Inositol-1-monophosphatase

1

2

High-throughput

0.479

High

1196974

Q86BB4
Transforming acidic coiled-coil protein, isoform E

1

1

High-throughput

0.479

High

1197106

Q86BM5
A kinase anchor protein 200, isoform D

1

2

High-throughput

0.479

High

1197511

LIG
Protein lingerer

1

7

High-throughput

0.479

High

1213523

HSP72
Major heat shock 70 kDa protein Ba

1

16

High-throughput

0.479

High

1229138

LVA
Protein lava lamp

1

20

High-throughput

0.479

High

1358864

RUVB2
RuvB-like helicase 2

1

8

High-throughput

0.479

High

1358959

PRDX2
Peroxiredoxin 2

1

2

High-throughput

0.479

High

1364794

Q9VEN9
Protein associated with topo II related-1, isoform A

1

3

High-throughput

0.479

High

1365056

HSP74
Major heat shock 70 kDa protein Bbb

1

16

High-throughput

0.479

High

1365058

RUVB1
RuvB-like helicase 1

1

8

High-throughput

0.479

High

1365060

Q9VHL2
T-complex protein 1 subunit eta

1

20

High-throughput

0.479

High

1365065

SOYB
Putative ATP-dependent RNA helicase SoYb

1

7

High-throughput

0.479

High

1365067

CH60C
60 kDa heat shock protein homolog 2, mitochondrial

1

17

High-throughput

0.479

High

1365069

Q9VP57
LD15904p

1

2

High-throughput

0.479

High

1365072

Q9VRL8
Blanks

1

3

High-throughput

0.479

High

1365075

FRL
Formin-like protein

1

1

High-throughput

0.479

High

1365076

AGO2
Protein argonaute-2

1

2

High-throughput

0.479

High

1365077

Q9VUU7
GEO09665p1

1

1

High-throughput

0.479

High

1365078

Q9VUU8
MIP04739p

1

1

High-throughput

0.479

High

1365082

CREBB
Cyclic AMP response element-binding protein B

1

2

High-throughput

0.479

High

1365083

NU153
Nuclear pore complex protein Nup153

1

14

High-throughput

0.479

High

1365084

Q9VXQ5
T-complex protein 1 subunit zeta

1

14

High-throughput

0.479

High

1365085

Q9VY76
AMP deaminase

1

1

High-throughput

0.479

High

1365091

Q9W1H5
Decapping protein 1, isoform A

1

1

High-throughput

0.479

High

1365098

Q9W392
T-complex protein 1 subunit beta

1

20

High-throughput

0.479

High

90862

E1JIM0
Non-specific lethal 1, isoform E

1

0

High-throughput

0.458

High

186000

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.458

High

590030

OTE
Otefin

1

0

High-throughput

0.458

High

677749

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

902204

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.458

High

1177397

Q7JVK8
GEO08987p1

1

0

High-throughput

0.458

High

1179518

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.458

High

1180014

DGT5
Augmin complex subunit dgt5

1

0

High-throughput

0.458

High

1213875

Q8IP79
ethanolamine-phosphate cytidylyltransferase

1

0

High-throughput

0.458

High

1250446

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

0

High-throughput

0.458

High

1280584

BCL9
Protein BCL9 homolog

1

0

High-throughput

0.458

High

1337047

JUPIT
Microtubule-associated protein Jupiter

1

0

High-throughput

0.458

High

1359426

Q9V406
Activator protein 4

1

0

High-throughput

0.458

High

1362421

MOC2B
Molybdopterin synthase catalytic subunit

1

0

High-throughput

0.458

High

1363180

VRET
Protein vreteno

1

0

High-throughput

0.458

High

1365066

CUP
Protein cup

1

0

High-throughput

0.458

High

1365081

Q9VWP5
Hat-trick, isoform D

1

0

High-throughput

0.458

High

1365092

Q9W1Q8
Translation initiation factor eIF2B subunit delta

1

0

High-throughput

0.458

High

247006

TENM
Teneurin-m

1

4

High-throughput

0.445

High

1365101

4EBP
Eukaryotic translation initiation factor 4E-binding protein

1

1

High-throughput

0.445

High

52444

A1Z7K2
FI03455p

1

12

High-throughput

0.437

High

54853

ZASP
PDZ and LIM domain protein Zasp

1

9

High-throughput

0.437

High

66162

A8JUU3
Secretory 16, isoform D

1

9

High-throughput

0.437

High

114122

M9PBC6
Bub3 interacting GLEBS and zinc finger domain protein, isoform F

1

3

High-throughput

0.437

High

332560

O97102
Small ubiquitin-related modifier

1

6

High-throughput

0.437

High

399195

EF1A2
Elongation factor 1-alpha 2

1

8

High-throughput

0.437

High

759525

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.437

High

780919

RL13
Large ribosomal subunit protein eL13

1

2

High-throughput

0.437

High

803324

RL7A
Large ribosomal subunit protein eL8

1

4

High-throughput

0.437

High

814198

TAF4
Transcription initiation factor TFIID subunit 4

1

1

High-throughput

0.437

High

816476

RL23
Large ribosomal subunit protein uL14

1

3

High-throughput

0.437

High

840178

MSL3
Protein male-specific lethal-3

1

1

High-throughput

0.437

High

842184

RL9
Large ribosomal subunit protein uL6

1

1

High-throughput

0.437

High

842229

RL22
Large ribosomal subunit protein eL22

1

3

High-throughput

0.437

High

987896

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.437

High

1180378

Q7K581
SD01637p

1

3

High-throughput

0.437

High

1213567

SLE
Protein slender lobes

1

7

High-throughput

0.437

High

1277076

VDAC
Voltage-dependent anion-selective channel

1

2

High-throughput

0.437

High

1353664

NH2L1
NHP2-like protein 1 homolog

1

4

High-throughput

0.437

High

1359882

HCF
Host cell factor

1

13

High-throughput

0.437

High

1361160

S39AD
Zinc transporter ZIP13 homolog

1

2

High-throughput

0.437

High

1361246

Q9VAJ2
Bub3, isoform A

1

13

High-throughput

0.437

High

1361709

RING1
E3 ubiquitin-protein ligase RING1

1

10

High-throughput

0.437

High

1362374

Q9VBU9
40S ribosomal protein S27

1

1

High-throughput

0.437

High

1365057

SLEL
Slender lobes-like protein

1

1

High-throughput

0.437

High

1365062

Q9VJD1
Glucosidase 2 subunit beta

1

2

High-throughput

0.437

High

1365070

Q9VPU7
Arouser, isoform C

1

17

High-throughput

0.437

High

1365073

Q9VS86
Peptidase S1 domain-containing protein

1

4

High-throughput

0.437

High

1365074

Q9VUB5
UpSET, isoform A

1

1

High-throughput

0.437

High

1365080

RS10B
Small ribosomal subunit protein eS10B

1

1

High-throughput

0.437

High

1365087

Q9VZB5
MIP31077p

1

1

High-throughput

0.437

High

1365088

Q9VZF2
LD05244p

1

5

High-throughput

0.437

High

1365089

Q9W0A8
FI01658p

1

1

High-throughput

0.437

High

1365093

NU214
Nuclear pore complex protein Nup214

1

4

High-throughput

0.437

High

1365094

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.437

High

1365096

Q9W2U7
LP18708p

1

7

High-throughput

0.437

High

1365099

Q9W3V2
FI19713p1

1

20

High-throughput

0.437

High

1098722

NETB
Netrin-B

1

2

High-throughput

0.407

High

55423

A1ZAU6
FI05912p

1

0

High-throughput

0.249

Low

137476

PSN
Presenilin homolog

1

0

High-throughput

0.249

Low

435984

CO4A1
Collagen alpha-1(IV) chain

1

0

High-throughput

0.249

Low

570453

RS17
Small ribosomal subunit protein eS17

1

0

High-throughput

0.249

Low

734340

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

780590

PEP
Zinc finger protein on ecdysone puffs

1

0

High-throughput

0.249

Low

836191

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.249

Low

878857

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

948964

STIM
Stromal interaction molecule homolog

1

0

High-throughput

0.249

Low

1179015

Q7K180
LD02709p

1

0

High-throughput

0.249

Low

1180764

Q7KLX3
Translocon-associated protein subunit delta

1

0

High-throughput

0.249

Low

1248674

Q8SX89
Kugelkern, isoform A

1

0

High-throughput

0.249

Low

1249300

Q8SYU0
Coiled-coil domain-containing protein 43

1

0

High-throughput

0.249

Low

1278620

CATL
Cathepsin L

1

0

High-throughput

0.249

Low

1360772

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

High-throughput

0.249

Low

1365054

Q9VFF0
GH01077p

1

0

High-throughput

0.249

Low

1365059

Q9VHH8
Beag

1

0

High-throughput

0.249

Low

1365061

Q9VHT6
Uncharacterized protein, isoform A

1

0

High-throughput

0.249

Low

1365064

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.249

Low

1365068

Q9VNA3
GH21273p

1

0

High-throughput

0.249

Low

1365086

Q9VZ00
FI19420p1

1

0

High-throughput

0.249

Low

1365090

Q9W1B9
Large ribosomal subunit protein uL11

1

0

High-throughput

0.249

Low

1365095

Q9W2I4
FI01566p

1

0

High-throughput

0.249

Low

1365097

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.249

Low

1365100

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.249

Low

1365079

FRIZ2
Frizzled-2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024