Protein: DRB1
HLA class II histocompatibility antigen, DRB1 beta chain (Human leukocyte antigen DRB1) (HLA-DRB1)

Gene: DRB1, HLA-DRB1
Organism: Homo sapiens
Interactions: 105
UniProt ID: P01911

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001772 - immunological synapse
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0001934 - positive regulation of protein phosphorylation
GO:0002437 - inflammatory response to antigenic stimulus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

354652

DRA
HLA class II histocompatibility antigen, DR alpha chain

3

18

Small-scale

0.834

High

354966

RN149
E3 ubiquitin-protein ligase RNF149

2

12

High-throughput

0.712

High

234734

MPZL2
Myelin protein zero-like protein 2

1

12

High-throughput

0.575

High

354918

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

18

High-throughput

0.575

High

354919

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

18

High-throughput

0.575

High

354921

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

19

High-throughput

0.575

High

354922

CD1A
T-cell surface glycoprotein CD1a

1

20

High-throughput

0.575

High

354925

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

20

High-throughput

0.575

High

354926

HLAE
HLA class I histocompatibility antigen, alpha chain E

1

20

High-throughput

0.575

High

354928

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

20

High-throughput

0.575

High

354931

DMA
HLA class II histocompatibility antigen, DM alpha chain

1

19

Small-scale

0.575

High

354932

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

20

High-throughput

0.575

High

354940

IDD
Integral membrane protein DGCR2/IDD

1

5

High-throughput

0.575

High

354954

DRB5
HLA class II histocompatibility antigen, DR beta 5 chain

1

20

High-throughput

0.575

High

354967

CADM4
Cell adhesion molecule 4

1

5

High-throughput

0.575

High

354970

NEUFC
Neuferricin

1

3

High-throughput

0.575

High

354971

BT2A2
Butyrophilin subfamily 2 member A2

1

10

High-throughput

0.575

High

354975

HMR1
Major histocompatibility complex class I-related gene protein

1

20

High-throughput

0.575

High

354990

SIRPD
Signal-regulatory protein delta

1

1

High-throughput

0.575

High

354998

CA2D2
Voltage-dependent calcium channel subunit alpha-2/delta-2

1

2

High-throughput

0.575

High

355002

BTNL2
Butyrophilin-like protein 2

1

14

High-throughput

0.575

High

355004

CLC4E
C-type lectin domain family 4 member E

1

7

High-throughput

0.575

High

354946

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

2

1

High-throughput

0.552

High

354999

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

2

7

High-throughput

0.552

High

354924

HS71A
Heat shock 70 kDa protein 1A

1

7

Small-scale

0.501

High

58780

T131L
Transmembrane protein 131-like

1

6

High-throughput

0.445

High

160892

RAB7L
Ras-related protein Rab-7L1

1

9

High-throughput

0.445

High

167794

NPC1
NPC intracellular cholesterol transporter 1

1

3

High-throughput

0.445

High

197119

SIA8C
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3

1

11

High-throughput

0.445

High

318337

ECEL1
Endothelin-converting enzyme-like 1

1

9

High-throughput

0.445

High

320756

SEM4F
Semaphorin-4F

1

11

High-throughput

0.445

High

354920

HG2A
HLA class II histocompatibility antigen gamma chain

1

8

High-throughput

0.445

High

354923

NEP
Neprilysin

1

9

Small-scale

0.445

High

354927

PERF
Perforin-1

1

1

High-throughput

0.445

High

354929

CD9
CD9 antigen

1

9

Small-scale

0.445

High

354930

ITA6
Integrin alpha-6

1

4

High-throughput

0.445

High

354933

SCNNA
Amiloride-sensitive sodium channel subunit alpha

1

12

High-throughput

0.445

High

354935

AT12A
Potassium-transporting ATPase alpha chain 2

1

11

High-throughput

0.445

High

354942

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

16

High-throughput

0.445

High

354943

NRG1
Pro-neuregulin-1, membrane-bound isoform

1

5

High-throughput

0.445

High

354944

NUCB1
Nucleobindin-1

1

2

High-throughput

0.445

High

354945

RON
Macrophage-stimulating protein receptor

1

20

High-throughput

0.445

High

354947

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

11

High-throughput

0.445

High

354949

STAR3
StAR-related lipid transfer protein 3

1

2

High-throughput

0.445

High

354950

NOMO1
BOS complex subunit NOMO1

1

2

High-throughput

0.445

High

354951

PON2
Serum paraoxonase/arylesterase 2

1

3

High-throughput

0.445

High

354953

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

5

High-throughput

0.445

High

354955

TBB8
Tubulin beta-8 chain

1

3

High-throughput

0.445

High

354956

GXLT1
Glucoside xylosyltransferase 1

1

5

High-throughput

0.445

High

354959

TGO1
Transport and Golgi organization protein 1 homolog

1

2

High-throughput

0.445

High

354961

TBA1A
Tubulin alpha-1A chain

1

7

High-throughput

0.445

High

354962

GALT5
Polypeptide N-acetylgalactosaminyltransferase 5

1

10

High-throughput

0.445

High

354965

EMC5
ER membrane protein complex subunit 5

1

2

High-throughput

0.445

High

354968

TIP
T-cell immunomodulatory protein

1

3

High-throughput

0.445

High

354969

SCRB1
Scavenger receptor class B member 1

1

3

High-throughput

0.445

High

354972

ELYS
Protein ELYS

1

2

High-throughput

0.445

High

354973

TM131
Transmembrane protein 131

1

8

High-throughput

0.445

High

354976

T106A
Transmembrane protein 106A

1

15

High-throughput

0.445

High

354978

ASIC4
Acid-sensing ion channel 4

1

12

High-throughput

0.445

High

354983

CSTN3
Calsyntenin-3

1

7

High-throughput

0.445

High

354986

TMM59
Transmembrane protein 59

1

2

High-throughput

0.445

High

354987

ABCA2
ATP-binding cassette sub-family A member 2

1

5

High-throughput

0.445

High

354988

ADT4
ADP/ATP translocase 4

1

10

High-throughput

0.445

High

354991

CHST8
Carbohydrate sulfotransferase 8

1

8

High-throughput

0.445

High

354995

CNNM1
Metal transporter CNNM1

1

8

High-throughput

0.445

High

354996

T106B
Transmembrane protein 106B

1

15

High-throughput

0.445

High

354997

IMPA3
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase

1

1

High-throughput

0.445

High

355003

S39AA
Zinc transporter ZIP10

1

5

High-throughput

0.445

High

355005

AT1B4
Protein ATP1B4

1

6

High-throughput

0.445

High

355006

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

7

High-throughput

0.445

High

354941

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.438

High

183345

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

0

High-throughput

0.426

High

199997

GPAA1
Glycosylphosphatidylinositol anchor attachment 1 protein

1

0

High-throughput

0.426

High

233971

NMD3B
Glutamate receptor ionotropic, NMDA 3B

1

0

High-throughput

0.426

High

354938

CCG7
Voltage-dependent calcium channel gamma-7 subunit

1

0

High-throughput

0.426

High

354948

ERG1
Squalene monooxygenase

1

0

High-throughput

0.426

High

354963

K2013
Uncharacterized protein KIAA2013

1

0

High-throughput

0.426

High

354964

K319L
Dyslexia-associated protein KIAA0319-like protein

1

0

High-throughput

0.426

High

354981

PIGS
GPI transamidase component PIG-S

1

0

High-throughput

0.426

High

354982

RNF5
E3 ubiquitin-protein ligase RNF5

1

0

High-throughput

0.426

High

354984

EMC6
ER membrane protein complex subunit 6

1

0

High-throughput

0.426

High

306498

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

1

1

High-throughput

0.407

High

315175

CNEP1
CTD nuclear envelope phosphatase 1

1

1

High-throughput

0.407

High

354934

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

2

High-throughput

0.407

High

354939

SSBP2
Single-stranded DNA-binding protein 2

1

3

High-throughput

0.407

High

354952

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

1

High-throughput

0.407

High

354957

MPPE1
Metallophosphoesterase 1

1

1

High-throughput

0.407

High

354958

MKS3
Meckelin

1

4

High-throughput

0.407

High

354960

TM201
Transmembrane protein 201

1

2

High-throughput

0.407

High

354974

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

12

High-throughput

0.407

High

354977

SARAF
Store-operated calcium entry-associated regulatory factor

1

5

High-throughput

0.407

High

354979

TECT2
Tectonic-2

1

6

High-throughput

0.407

High

354980

P121A
Nuclear envelope pore membrane protein POM 121

1

4

High-throughput

0.407

High

354985

T106C
Transmembrane protein 106C

1

15

High-throughput

0.407

High

354989

RAB6C
Ras-related protein Rab-6C

1

6

High-throughput

0.407

High

354992

UD17
UDP-glucuronosyltransferase 1A7

1

6

High-throughput

0.407

High

354993

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.407

High

355000

EXTL2
Exostosin-like 2

1

5

High-throughput

0.407

High

355001

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

1

High-throughput

0.407

High

354994

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.238

Low

210707

NDUA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

1

0

High-throughput

0.232

Low

306445

NDUB4
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4

1

0

High-throughput

0.232

Low

354936

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

0

High-throughput

0.232

Low

354937

NDUA6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024