Protein: FWCH1
FLYWCH-type zinc finger-containing protein 1

Gene: FWCH1, FLYWCH1
Organism: Homo sapiens
Interactions: 33
UniProt ID: Q4VC44

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001223 - transcription coactivator binding
GO:0003677 - DNA binding
GO:0003714 - transcription corepressor activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

269222

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

1090686

TRAF2
TNF receptor-associated factor 2

2

0

High-throughput

0.580

High

1196962

HOOK2
Protein Hook homolog 2

2

0

High-throughput

0.580

High

1196968

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

396245

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

1139724

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

High-throughput

0.518

High

340896

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

0

High-throughput

0.513

High

913507

KIF11
Kinesin-like protein KIF11

1

0

High-throughput

0.513

High

225299

HTSF1
17S U2 SnRNP complex component HTATSF1

1

0

High-throughput

0.493

High

998385

H31
Histone H3.1

1

1

High-throughput

0.479

High

1129615

MDC1
Mediator of DNA damage checkpoint protein 1

1

1

High-throughput

0.479

High

487384

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

799181

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

979761

H4
Histone H4

1

0

High-throughput

0.458

High

1004647

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1137744

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.458

High

1196961

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.458

High

1196969

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1196958

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

65061

GG6L9
Golgin subfamily A member 6-like protein 9

2

0

High-throughput

0.316

High

895729

LHX2
LIM/homeobox protein Lhx2

2

0

High-throughput

0.316

High

1196957

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

0

High-throughput

0.316

High

1196959

CC125
Coiled-coil domain-containing protein 125

2

0

High-throughput

0.316

High

1196963

GMCL1
Germ cell-less protein-like 1

2

0

High-throughput

0.316

High

1196965

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

2

0

High-throughput

0.316

High

1196966

KIFC3
Kinesin-like protein KIFC3

2

0

High-throughput

0.316

High

251905

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

0

High-throughput

0.279

Low

426509

HMGN2
Non-histone chromosomal protein HMG-17

1

0

High-throughput

0.269

Low

1196964

CC136
Coiled-coil domain-containing protein 136

1

0

High-throughput

0.251

Low

1196960

CCD71
Coiled-coil domain-containing protein 71

1

0

Small-scale

0.249

Low

1196967

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

641609

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

0

High-throughput

0.238

Low

344213

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025