Protein: GHC2
Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+) symporter 2) (Solute carrier family 25 member 18)

Gene: GHC2, SLC25A18
Organism: Homo sapiens
Interactions: 42
UniProt ID: Q9H1K4

Gene Ontology (top 5):
GO:0005280 - amino acid:proton symporter activity
GO:0005313 - L-glutamate transmembrane transporter activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006811 - monoatomic ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1431153

GHC1
Mitochondrial glutamate carrier 1

6

15

High-throughput

0.940

High

486708

FGR
Tyrosine-protein kinase Fgr

2

6

High-throughput

0.571

High

70473

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.553

High

1419008

KRA93
Keratin-associated protein 9-3

2

4

High-throughput

0.553

High

532956

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.536

High

1093421

TRI32
E3 ubiquitin-protein ligase TRIM32

1

7

High-throughput

0.536

High

1123423

ICT1
Large ribosomal subunit protein mL62

1

6

High-throughput

0.536

High

1431154

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

9

High-throughput

0.523

High

440204

LCK
Tyrosine-protein kinase Lck

2

6

High-throughput

0.521

High

1097114

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

2

9

High-throughput

0.521

High

537890

HSP7C
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.489

High

997128

TBA4A
Tubulin alpha-4A chain

1

13

High-throughput

0.489

High

1230808

ANR40
Ankyrin repeat domain-containing protein 40

1

1

High-throughput

0.489

High

1339846

PJA1
E3 ubiquitin-protein ligase Praja-1

1

4

High-throughput

0.489

High

1395111

TMX3
Protein disulfide-isomerase TMX3

1

5

High-throughput

0.489

High

1399740

RBM14
RNA-binding protein 14

1

1

High-throughput

0.489

High

1431157

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

1

High-throughput

0.489

High

1431160

CE164
Centrosomal protein of 164 kDa

1

8

High-throughput

0.489

High

1431161

DICER
Endoribonuclease Dicer

1

8

High-throughput

0.489

High

1431162

DMXL1
DmX-like protein 1

1

7

High-throughput

0.489

High

766840

PHB1
Prohibitin 1

1

13

High-throughput

0.479

High

1280490

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

10

High-throughput

0.479

High

156339

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

1

High-throughput

0.470

High

777763

VGFR3
Vascular endothelial growth factor receptor 3

1

3

High-throughput

0.457

High

157838

CTRO
Citron Rho-interacting kinase

1

11

High-throughput

0.437

High

905130

MECP2
Methyl-CpG-binding protein 2

1

7

High-throughput

0.437

High

920268

PLK1
Serine/threonine-protein kinase PLK1

1

5

High-throughput

0.437

High

1135811

HAPR1
HUWE1-associated protein modifying stress responses 1

1

1

High-throughput

0.437

High

1138045

TNIP1
TNFAIP3-interacting protein 1

1

12

High-throughput

0.437

High

1197705

MIDN
Midnolin

1

6

High-throughput

0.437

High

1255491

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1393684

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.437

High

1431155

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

4

High-throughput

0.437

High

1431156

ANLN
Anillin

1

6

High-throughput

0.437

High

1335716

MOT11
Monocarboxylate transporter 11

1

9

High-throughput

0.407

High

1186859

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.316

High

1198050

KR132
Keratin-associated protein 13-2

2

0

High-throughput

0.316

High

1431158

ZNHI2
Zinc finger HIT domain-containing protein 2

1

0

High-throughput

0.279

Low

1431159

ANGE1
Protein angel homolog 1

1

0

High-throughput

0.279

Low

339585

ACSL3
Fatty acid CoA ligase Acsl3

1

0

High-throughput

0.249

Low

1211713

FA83B
Protein FAM83B

1

0

High-throughput

0.232

Low

1417921

K1671
Uncharacterized protein KIAA1671

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025