Protein: ATRIP
ATR-interacting protein (ATM and Rad3-related-interacting protein)

Gene: ATRIP
Organism: Homo sapiens
Interactions: 97
UniProt ID: Q8WXE1

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006139 - nucleobase-containing compound metabolic process
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1109480

ATR
Serine/threonine-protein kinase ATR

27

5

Small-scale

0.768

High

696057

RFA1
Replication protein A 70 kDa DNA-binding subunit

15

0

Small-scale

0.727

High

589271

RFA2
Replication protein A 32 kDa subunit

6

0

Small-scale

0.692

High

799335

BRCA1
Breast cancer type 1 susceptibility protein

3

2

Small-scale

0.660

High

1360335

TOPB1
DNA topoisomerase 2-binding protein 1

3

1

Small-scale

0.646

High

1360347

CINP
Cyclin-dependent kinase 2-interacting protein

2

0

Small-scale

0.633

High

888210

MCM2
DNA replication licensing factor MCM2

2

4

Small-scale

0.624

High

768757

RFA3
Replication protein A 14 kDa subunit

3

0

Small-scale

0.619

High

262103

NBN
Nibrin

3

0

Small-scale

0.613

High

1360356

FZD10
Frizzled-10

2

0

High-throughput

0.602

High

278916

PEX14
Peroxisomal membrane protein PEX14

2

0

High-throughput

0.585

High

1326199

PNKD
Probable thioesterase PNKD

2

0

High-throughput

0.585

High

1360357

TIM
Protein timeless homolog

2

0

Small-scale

0.585

High

756285

MCM7
DNA replication licensing factor MCM7

2

3

Small-scale

0.584

High

1218944

TASO2
Protein TASOR 2

1

1

High-throughput

0.573

High

1360352

ETAA1
Ewing's tumor-associated antigen 1

2

0

Small-scale

0.569

High

1360334

ATRIP
ATR-interacting protein

2

0

Small-scale

0.561

High

669954

MCM3
DNA replication licensing factor MCM3

1

4

Small-scale

0.561

High

755989

MCM5
DNA replication licensing factor MCM5

1

3

Small-scale

0.561

High

1102214

ATM
Serine-protein kinase ATM

1

5

Small-scale

0.561

High

1128245

MCM6
DNA replication licensing factor MCM6

1

4

Small-scale

0.561

High

180350

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.549

High

221166

SPY2
Protein sprouty homolog 2

1

0

High-throughput

0.549

High

633413

MX2
Interferon-induced GTP-binding protein Mx2

1

0

High-throughput

0.549

High

1360262

MT21A
Protein N-lysine methyltransferase METTL21A

1

0

High-throughput

0.549

High

1360355

CDC23
Cell division cycle protein 23 homolog

1

0

High-throughput

0.549

High

229350

ZBT14
Zinc finger and BTB domain-containing protein 14

1

0

Small-scale

0.537

High

1312357

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

0

Small-scale

0.537

High

1360358

CE164
Centrosomal protein of 164 kDa

1

0

Small-scale

0.537

High

897913

CDK9
Cyclin-dependent kinase 9

1

0

Small-scale

0.530

High

1360351

FANCL
E3 ubiquitin-protein ligase FANCL

1

0

Small-scale

0.529

High

221466

OX2R
Orexin receptor type 2

1

0

High-throughput

0.513

High

424440

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.513

High

426544

HMGN2
Non-histone chromosomal protein HMG-17

1

0

High-throughput

0.513

High

854191

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

946843

H2B1D
Histone H2B type 1-D

1

0

High-throughput

0.513

High

1042768

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

0

High-throughput

0.513

High

1274037

PHF5A
PHD finger-like domain-containing protein 5A

1

0

High-throughput

0.513

High

1310267

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1008258

PRKDC
DNA-dependent protein kinase catalytic subunit

1

5

Small-scale

0.501

High

1360362

NEMO
NF-kappa-B essential modulator

1

0

Small-scale

0.493

High

210414

MTLR
Motilin receptor

1

2

High-throughput

0.489

High

719823

V2R
Vasopressin V2 receptor

1

1

High-throughput

0.489

High

1101610

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

1

High-throughput

0.489

High

1360342

CML1
Chemerin-like receptor 1

1

2

High-throughput

0.489

High

1025576

CDK16
Cyclin-dependent kinase 16

1

1

High-throughput

0.481

High

1360341

CDC6
Cell division control protein 6 homolog

1

0

Small-scale

0.480

High

1360343

Q9BRL4
cyclin-dependent kinase

1

1

High-throughput

0.470

High

1081765

FP100
Fanconi anemia core complex-associated protein 100

1

0

Small-scale

0.460

High

218548

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

298612

RAD17
Cell cycle checkpoint protein RAD17

1

0

Small-scale

0.458

High

342986

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

Small-scale

0.458

High

846642

MSH2
DNA mismatch repair protein Msh2

1

0

Small-scale

0.458

High

892904

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.458

High

1088929

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1229178

INT3
Integrator complex subunit 3

1

0

Small-scale

0.458

High

1273221

RIR2B
Ribonucleoside-diphosphate reductase subunit M2 B

1

0

Small-scale

0.458

High

1360336

RAD50
DNA repair protein RAD50

1

0

Small-scale

0.458

High

1360340

NEK1
Serine/threonine-protein kinase Nek1

1

0

Small-scale

0.458

High

1360344

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

0

Small-scale

0.458

High

1360346

TIPIN
TIMELESS-interacting protein

1

0

Small-scale

0.458

High

1360348

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.458

High

1360361

TELO2
Telomere length regulation protein TEL2 homolog

1

0

Small-scale

0.458

High

1360350

RIBC2
RIB43A-like with coiled-coils protein 2

1

0

High-throughput

0.438

High

1360338

SPSB1
SPRY domain-containing SOCS box protein 1

1

1

Small-scale

0.437

High

587356

SIAT1
Beta-galactoside alpha-2,6-sialyltransferase 1

2

0

High-throughput

0.328

High

749245

CD70
CD70 antigen

2

0

High-throughput

0.328

High

850884

KI3L2
Killer cell immunoglobulin-like receptor 3DL2

2

0

High-throughput

0.328

High

1360337

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

2

0

High-throughput

0.328

High

1313666

IFT20
Intraflagellar transport protein 20 homolog

2

0

High-throughput

0.316

High

364167

MOS
Proto-oncogene serine/threonine-protein kinase mos

1

0

High-throughput

0.299

High

562987

SCG2
Secretogranin-2

1

0

High-throughput

0.299

High

1241227

CA094
Uncharacterized protein C1orf94

1

0

High-throughput

0.299

High

1336557

FA156
Protein FAM156A/FAM156B

1

0

High-throughput

0.299

High

1348390

LNX1
E3 ubiquitin-protein ligase LNX

1

0

High-throughput

0.299

High

1360345

CC28B
Coiled-coil domain-containing protein 28B

1

0

High-throughput

0.299

High

1360354

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

0

High-throughput

0.299

High

209081

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.279

Low

303689

JTB
Protein JTB

1

0

High-throughput

0.279

Low

479452

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.279

Low

821167

TXLNA
Alpha-taxilin

1

0

High-throughput

0.279

Low

914311

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

1227157

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.279

Low

1245894

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.279

Low

1281711

B3GN8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

1

0

High-throughput

0.279

Low

1360339

ARL8A
ADP-ribosylation factor-like protein 8A

1

0

High-throughput

0.279

Low

1360349

FXYD6
FXYD domain-containing ion transport regulator 6

1

0

High-throughput

0.279

Low

1360353

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

272349

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

1276250

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.249

Low

1360360

DAAM1
Disheveled-associated activator of morphogenesis 1

1

0

High-throughput

0.249

Low

50641

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

166368

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.232

Low

171534

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.232

Low

516772

SCHI1
Schwannomin-interacting protein 1

1

0

High-throughput

0.232

Low

1360359

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025