Protein: ERI1
3'-5' exoribonuclease 1 (EC 3.1.13.1) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-end-specific exoribonuclease) (Histone mRNA 3'-exonuclease 1) (Protein 3'hExo) (HEXO)

Gene: ERI1
Organism: Homo sapiens
Interactions: 48
UniProt ID: Q8IV48

Gene Ontology (top 5):
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000460 - maturation of 5.8S rRNA
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

848794

MAGAA
Melanoma-associated antigen 10

4

1

High-throughput

0.691

High

1126825

SLBP
Histone RNA hairpin-binding protein

2

0

Small-scale

0.581

High

1016093

RL19
Large ribosomal subunit protein eL19

2

0

High-throughput

0.576

High

372495

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

1308436

LN28A
Protein lin-28 homolog A

2

2

High-throughput

0.552

High

295205

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

0

High-throughput

0.513

High

431181

LA
Lupus La protein

1

0

High-throughput

0.513

High

969961

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

973494

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.513

High

992842

RACK1
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.513

High

1308428

CDCA5
Sororin

1

0

High-throughput

0.513

High

1308438

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.513

High

1308440

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.513

High

1308431

PHB2
Prohibitin-2

1

0

High-throughput

0.493

High

72421

MI4GD
MIF4G domain-containing protein

1

0

Small-scale

0.484

High

185835

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

173031

XPO1
Exportin-1

1

2

High-throughput

0.479

High

1254514

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1308435

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1308437

BRD7
Bromodomain-containing protein 7

1

1

High-throughput

0.479

High

1308439

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.479

High

822744

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.460

High

132147

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

973760

RUXE
Small nuclear ribonucleoprotein E

1

0

High-throughput

0.458

High

1067489

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1276446

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1308433

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

191699

MAGB2
Melanoma-associated antigen B2

1

1

High-throughput

0.445

High

1252456

LN28B
Protein lin-28 homolog B

1

2

High-throughput

0.445

High

1308441

YBOX2
Y-box-binding protein 2

1

2

High-throughput

0.445

High

601759

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.426

High

658262

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.426

High

809713

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.426

High

860826

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.426

High

977294

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.426

High

1037250

H11
Histone H1.1

1

0

High-throughput

0.426

High

1112077

KRR1
KRR1 small subunit processome component homolog

1

0

High-throughput

0.426

High

1308432

PYM1
Partner of Y14 and mago

1

0

High-throughput

0.426

High

1308434

ZN692
Zinc finger protein 692

1

0

High-throughput

0.426

High

605521

SYN1
Synapsin-1

1

0

High-throughput

0.279

Low

879250

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

1308426

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1009241

PRR3
Proline-rich protein 3

1

0

High-throughput

0.232

Low

1234440

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.232

Low

1308425

CA174
UPF0688 protein C1orf174

1

0

High-throughput

0.232

Low

1308427

ZCRB1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1

1

0

High-throughput

0.232

Low

1308429

C170L
Cep170-like protein

1

0

High-throughput

0.232

Low

1308430

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025