Protein: HACD1
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 1) (HACD1) (Cementum-attachment protein) (CAP) (Protein-tyrosine phosphatase-like member A)

Gene: HACD1
Organism: Homo sapiens
Interactions: 25
UniProt ID: B0YJ81

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0010811 - positive regulation of cell-substrate adhesion
GO:0016020 - membrane
GO:0018812 - 3-hydroxyacyl-CoA dehydratase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

72868

S15A1
Solute carrier family 15 member 1

2

2

High-throughput

0.628

High

72861

SEMG1
Semenogelin-1

3

1

High-throughput

0.609

High

72872

SEMG2
Semenogelin-2

3

1

High-throughput

0.609

High

72881

TECR
Very-long-chain enoyl-CoA reductase

2

1

High-throughput

0.606

High

72878

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

2

0

High-throughput

0.602

High

72876

RN170
E3 ubiquitin-protein ligase RNF170

2

0

High-throughput

0.580

High

72879

T106C
Transmembrane protein 106C

2

0

High-throughput

0.580

High

72873

I10R1
Interleukin-10 receptor subunit alpha

2

1

High-throughput

0.553

High

72862

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.536

High

72863

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.536

High

72865

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

4

High-throughput

0.536

High

72866

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

6

High-throughput

0.536

High

72867

PHB1
Prohibitin 1

1

2

High-throughput

0.536

High

72869

XPO2
Exportin-2

1

1

High-throughput

0.536

High

72870

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

2

High-throughput

0.536

High

72858

XPO1
Exportin-1

1

0

High-throughput

0.513

High

72871

TPM4
Tropomyosin alpha-4 chain

1

0

High-throughput

0.513

High

72864

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

72877

PHB2
Prohibitin-2

1

2

High-throughput

0.489

High

72880

S22A4
Solute carrier family 22 member 4

1

3

High-throughput

0.489

High

72882

COR1C
Coronin-1C

1

1

High-throughput

0.489

High

72875

SSMM1
Serine-rich single-pass membrane protein 1

1

0

High-throughput

0.426

High

72874

CPLX4
Complexin-4

2

0

High-throughput

0.316

High

72859

MYO1B
Unconventional myosin-Ib

1

0

High-throughput

0.279

Low

72860

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025