Protein: CPLX4
Complexin-4 (Complexin IV) (CPX IV)

Gene: CPLX4
Organism: Homo sapiens
Interactions: 110
UniProt ID: Q7Z7G2

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0005886 - plasma membrane
GO:0007601 - visual perception
GO:0016079 - synaptic vesicle exocytosis
GO:0019905 - syntaxin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

328689

VAMP5
Vesicle-associated membrane protein 5

2

1

High-throughput

0.783

High

278523

VAMP4
Vesicle-associated membrane protein 4

2

0

High-throughput

0.742

High

1100684

STX3
Syntaxin-3

2

0

High-throughput

0.742

High

1281208

STX8
Syntaxin-8

2

0

High-throughput

0.742

High

280238

SC22B
Vesicle-trafficking protein SEC22b

2

0

High-throughput

0.655

High

213687

AQP9
Aquaporin-9

2

1

High-throughput

0.606

High

455917

ASGR1
Asialoglycoprotein receptor 1

2

1

High-throughput

0.606

High

1007398

S35A1
CMP-sialic acid transporter

2

1

High-throughput

0.606

High

1050034

PLP2
Proteolipid protein 2

2

1

High-throughput

0.606

High

1092779

MALL
MAL-like protein

2

1

High-throughput

0.606

High

1249706

CLC4G
C-type lectin domain family 4 member G

2

1

High-throughput

0.606

High

1281170

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

1

High-throughput

0.606

High

1281189

ZNT2
Proton-coupled zinc antiporter SLC30A2

2

1

High-throughput

0.606

High

540258

SPTB1
Spectrin beta chain, erythrocytic

2

0

High-throughput

0.602

High

691782

MK03
Mitogen-activated protein kinase 3

2

0

High-throughput

0.602

High

162222

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

2

0

High-throughput

0.580

High

216321

MGA
Maltase-glucoamylase

2

0

High-throughput

0.580

High

390910

TRFE
Serotransferrin

2

0

High-throughput

0.580

High

692220

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

2

0

High-throughput

0.580

High

715923

AQP1
Aquaporin-1

2

0

High-throughput

0.580

High

948868

CD81
CD81 antigen

2

0

High-throughput

0.580

High

1050855

DCE2
Glutamate decarboxylase 2

2

0

High-throughput

0.580

High

1055127

CCG1
Voltage-dependent calcium channel gamma-1 subunit

2

0

High-throughput

0.580

High

1126115

GRM2
Metabotropic glutamate receptor 2

2

0

High-throughput

0.580

High

1164218

AOC3
Amine oxidase [copper-containing] 3

2

0

High-throughput

0.580

High

1203115

SGMR2
Sigma intracellular receptor 2

2

0

High-throughput

0.580

High

1203707

TTMP
TPA-induced transmembrane protein

2

0

High-throughput

0.580

High

1208713

RTP2
Receptor-transporting protein 2

2

0

High-throughput

0.580

High

1216435

TSPO2
Translocator protein 2

2

0

High-throughput

0.580

High

1219804

PLPP4
Phospholipid phosphatase 4

2

0

High-throughput

0.580

High

1247360

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.580

High

1281174

NRAC
Nutritionally-regulated adipose and cardiac enriched protein homolog

2

0

High-throughput

0.580

High

1281176

CLDN2
Claudin domain-containing protein 2

2

0

High-throughput

0.580

High

1281200

S39A9
Zinc transporter ZIP9

2

0

High-throughput

0.580

High

1281202

AIG1
Androgen-induced gene 1 protein

2

0

High-throughput

0.580

High

1281203

CLN6
Ceroid-lipofuscinosis neuronal protein 6

2

0

High-throughput

0.580

High

1281204

NINJ2
Ninjurin-2

2

0

High-throughput

0.580

High

1281206

LPAR3
Lysophosphatidic acid receptor 3

2

0

High-throughput

0.580

High

1281209

T3JAM
TRAF3-interacting JNK-activating modulator

2

0

High-throughput

0.580

High

1281213

SELK
Selenoprotein K

2

0

High-throughput

0.580

High

636233

MAL
Myelin and lymphocyte protein

2

1

High-throughput

0.553

High

1281185

S35A4
Probable UDP-sugar transporter protein SLC35A4

2

1

High-throughput

0.553

High

1281199

TM14B
Transmembrane protein 14B

2

1

High-throughput

0.553

High

1281214

TM14A
Transmembrane protein 14A

2

1

High-throughput

0.553

High

537426

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.513

High

1202520

Q59EV6
Carboxypeptidase

1

1

High-throughput

0.470

High

74173

SMIM1
Small integral membrane protein 1

1

0

High-throughput

0.460

High

791495

SYUA
Alpha-synuclein

1

0

High-throughput

0.460

High

1281178

LHPL5
LHFPL tetraspan subfamily member 5 protein

1

0

High-throughput

0.460

High

528689

PPGB
Lysosomal protective protein

1

1

High-throughput

0.439

High

370209

CYTN
Cystatin-SN

2

0

High-throughput

0.328

High

853324

CBX5
Chromobox protein homolog 5

2

0

High-throughput

0.328

High

977742

ACTA
Actin, aortic smooth muscle

2

0

High-throughput

0.328

High

1281172

MICU2
Calcium uptake protein 2, mitochondrial

2

0

High-throughput

0.328

High

1281192

EFHD1
EF-hand domain-containing protein D1

2

0

High-throughput

0.328

High

1281195

IPPK
Inositol-pentakisphosphate 2-kinase

2

0

High-throughput

0.328

High

49664

T120B
Transmembrane protein 120B

2

0

High-throughput

0.316

High

60580

TM218
Transmembrane protein 218

2

0

High-throughput

0.316

High

72874

HACD1
Very-long-chain

2

0

High-throughput

0.316

High

209049

CYB5B
Cytochrome b5 type B

2

0

High-throughput

0.316

High

327332

ZFPL1
Zinc finger protein-like 1

2

0

High-throughput

0.316

High

336164

CNIH1
Protein cornichon homolog 1

2

0

High-throughput

0.316

High

341436

CDS2
Phosphatidate cytidylyltransferase 2

2

0

High-throughput

0.316

High

369976

CO5
Complement C5

2

0

High-throughput

0.316

High

423799

APOD
Apolipoprotein D

2

0

High-throughput

0.316

High

483926

HMOX1
Heme oxygenase 1

2

0

High-throughput

0.316

High

548045

PSPC
Surfactant protein C

2

0

High-throughput

0.316

High

688395

PPLA
Phospholamban

2

0

High-throughput

0.316

High

849015

PTN9
Tyrosine-protein phosphatase non-receptor type 9

2

0

High-throughput

0.316

High

894857

EMD
Emerin

2

0

High-throughput

0.316

High

928864

LIPR1
Inactive pancreatic lipase-related protein 1

2

0

High-throughput

0.316

High

944395

SYJ2B
Synaptojanin-2-binding protein

2

0

High-throughput

0.316

High

1005397

CP4F2
Cytochrome P450 4F2

2

0

High-throughput

0.316

High

1081676

TM267
Transmembrane protein 267

2

0

High-throughput

0.316

High

1092019

BNIP2
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

2

0

High-throughput

0.316

High

1127332

WFDC2
WAP four-disulfide core domain protein 2

2

0

High-throughput

0.316

High

1154996

ADIPO
Adiponectin

2

0

High-throughput

0.316

High

1195529

CTXN3
Cortexin-3

2

0

High-throughput

0.316

High

1209963

TM201
Transmembrane protein 201

2

0

High-throughput

0.316

High

1281171

NRM
Nurim

2

0

High-throughput

0.316

High

1281173

TM86A
Lysoplasmalogenase TMEM86A

2

0

High-throughput

0.316

High

1281175

T229B
Transmembrane protein 229B

2

0

High-throughput

0.316

High

1281177

CC4L
C-C motif chemokine 4-like

2

0

High-throughput

0.316

High

1281179

TM254
Transmembrane protein 254

2

0

High-throughput

0.316

High

1281180

GIMA1
GTPase IMAP family member 1

2

0

High-throughput

0.316

High

1281181

S35B4
Nucleotide sugar transporter SLC35B4

2

0

High-throughput

0.316

High

1281182

TM203
Transmembrane protein 203

2

0

High-throughput

0.316

High

1281183

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

0

High-throughput

0.316

High

1281184

YIPF6
Protein YIPF6

2

0

High-throughput

0.316

High

1281186

TMM19
Transmembrane protein 19

2

0

High-throughput

0.316

High

1281187

CYBC1
Cytochrome b-245 chaperone 1

2

0

High-throughput

0.316

High

1281188

VKOR1
Vitamin K epoxide reductase complex subunit 1

2

0

High-throughput

0.316

High

1281190

TMM79
Transmembrane protein 79

2

0

High-throughput

0.316

High

1281191

TM243
Transmembrane protein 243

2

0

High-throughput

0.316

High

1281193

DB127
Beta-defensin 127

2

0

High-throughput

0.316

High

1281194

TMM60
Transmembrane protein 60

2

0

High-throughput

0.316

High

1281196

HHATL
Protein-cysteine N-palmitoyltransferase HHAT-like protein

2

0

High-throughput

0.316

High

1281197

SMCO4
Single-pass membrane and coiled-coil domain-containing protein 4

2

0

High-throughput

0.316

High

1281201

S38A7
Sodium-coupled neutral amino acid transporter 7

2

0

High-throughput

0.316

High

1281205

ORML1
ORM1-like protein 1

2

0

High-throughput

0.316

High

1281207

PGAP2
Acyltransferase PGAP2

2

0

High-throughput

0.316

High

1281210

MA2B2
Epididymis-specific alpha-mannosidase

2

0

High-throughput

0.316

High

1281211

INSI2
Insulin-induced gene 2 protein

2

0

High-throughput

0.316

High

1281212

UBIA1
UbiA prenyltransferase domain-containing protein 1

2

0

High-throughput

0.316

High

335562

BMP10
Bone morphogenetic protein 10

1

0

High-throughput

0.251

Low

665990

IBP5
Insulin-like growth factor-binding protein 5

1

0

High-throughput

0.251

Low

1203316

TM128
Transmembrane protein 128

1

0

High-throughput

0.251

Low

1229429

TMM42
Transmembrane protein 42

1

0

High-throughput

0.251

Low

1249544

TM107
Transmembrane protein 107

1

0

High-throughput

0.251

Low

1281198

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025