Protein: GAB1
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)

Gene: GAB1
Organism: Mus musculus
Interactions: 17
UniProt ID: Q9QYY0

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005938 - cell cortex
GO:0006979 - response to oxidative stress

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1221262

GRB2
Growth factor receptor-bound protein 2

6

20

Small-scale

0.930

High

582014

NTRK2
BDNF/NT-3 growth factors receptor

1

20

Small-scale

0.691

High

767031

PTN11
Tyrosine-protein phosphatase non-receptor type 11

4

14

Small-scale

0.676

High

686988

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

3

20

Small-scale

0.664

High

313438

GRAP2
GRB2-related adaptor protein 2

1

20

Small-scale

0.647

High

1022230

SHC1
SHC-transforming protein 1

3

20

Small-scale

0.636

High

431376

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.618

High

591189

MET
Hepatocyte growth factor receptor

1

19

Small-scale

0.590

High

1223514

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

4

Small-scale

0.590

High

772099

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

Small-scale

0.575

High

107242

F8VQL0
Hepatocyte growth factor receptor

1

20

Small-scale

0.553

High

73967

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

3

Small-scale

0.479

High

1424234

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

3

Small-scale

0.479

High

1282037

Q80UI5
Phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1

1

20

Small-scale

0.462

High

1064959

RUNX2
Runt-related transcription factor 2

1

0

Small-scale

0.458

High

1240221

PPRC1
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

1

6

High-throughput

0.417

High

1341655

Q8R5B8
Crkl protein

1

20

Small-scale

0.417

High


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Last updated: 11Aug2025